Objective: The goal of this study was to utilize Gait Profile Score (GPS) and Deviation Index (GDI), assess its capability differentiating between injured non-injured runners. Design: In total, 45 long-distance runners (15 non-injured, 30 injured), diagnosed with one the following running related injuries, patella femoral pain syndrome, iliotibial medial tibial stress were recruited. Methods: D...

Das (Geo-) Datenmanagement hat für Projekte des nachhaltigen Landmanagements einen besonderen Stellenwert aufgrund der immanenten Interdisziplinarität. Da viele verschiedene Projektpartner auf einen Austausch von Daten angewiesen sind, sollten standardkonforme, webbasierte Geodateninfrastrukturen (GDI) zum Einsatz kommen. Im Beitrag wird die Software GeoNetwork OpenSource zur Errichtung einer G...

in this paper, the optimal location and characteristics of tadas dampers in moment resisting steel structures, considering the application of minimum number of tadas dampers in a building as an objective function and the restriction for destruction of main members is studied. genetic algorithm in first generation randomly produces different chromosomes representing unique tadas dampers distribu...

Intracellular vesicular trafficking is regulated by approximately 60 members of the Rab subfamily of small Ras-like GDP/GTP binding proteins. Rab proteins cycle between inactive and active states as well as between cytosolic and membrane bound forms. Membrane extraction/delivery and cytosolic distribution of Rabs is mediated by interaction with the protein GDP dissociation inhibitor (GDI) that ...

We examined the dose-related net effects of glucagon-like peptide 1 (GLP-1) on insulin secretion, insulin sensitivity, and glucose disposal as derived from the minimal model of glucose disappearance in anesthetized mice. GLP-1 dose dependently potentiated insulin secretion after glucose administration, with the half-maximal effect at 1 nmol/kg. GLP-1 also dose dependently reduced the area under...

This study investigated the gender differences in association of some behavioural and socioeconomic factors with obesity indices in a population-based sample of 12,514 Iranian adults. The mean body mass index (BMI), waist circumference (WC), and the waist-to-hip ratio (WHR) were significantly higher in women than in men. Current and passive smoking had an inverse association with BMI among male...

A novel regulatory protein for the rho proteins (rhoA p2 1 and rhoB p20), belonging to a ras p2 llras p21like small molecular weight (M,) GTP-binding protein (G protein) superfamily, was purified to near homogeneity from bovine brain cytosol and characterized. This regulatory protein, designated here as GDP dissociation inhibitor (GDI) for the rho proteins (rho GDI), inhibited the dissociation ...

VLSI technology has developed over the years thereby enhancing the performance of chips in terms of three basic constraints viz. delay, power and area. Gate Diffusion Input technique is one such method which attempts to minimize the delay and power consumed by the circuit. The paper basically focuses on the implementation of the technique on combinational logic circuits and experimental delay r...

rho GDP dissociation inhibitor (GDI) is an inhibitory GDP/GTP exchange protein for a group of small GTP-binding proteins including at least rhoA p21, rhoB p21, rac1 p21, rac2 p21, and G25K. Microinjection of rho GDI into Swiss 3T3 cells made the cells round and refractile. This morphological change was accompanied by the disappearance of stress fibers. The rho GDI action was prevented by comicr...

Bacterial pathogens deliver effector proteins with diverse biochemical activities into host cells, thereby modulating various host functions. Legionella pneumophila hijacks host vesicle trafficking to avoid phagosome-lysosome fusion, a mechanism that is dependent on the Legionella Dot/Icm type IV secretion system. SidM/DrrA, a Legionella type IV effector, is important for the interactions of Le...