venturi flumes are measurement structures commonly used in water systems to measure the flow discharge. some of them are not well installed or present some geometrical defects. the objective of this study is to investigate the hydraulic influence of a number of typical wrong installations and geometrical defects of long-throated venturi flumes: significant positive or adverse slopes, humps and ...

graphene sheet including single vacancy, double vacancy and stone-wales with armchair and zigzag structure was simulated using molecular dynamics simulation. the effect of defects on shear’s modulus, shear strength and fracture  strain was investigated. results showed that these shear properties reduce when the degrees of all kinds of defects increase. the dangling bond in sv and dv defected gr...

Regulation of MHC class II gene expression is an essential aspect of the control of the immune response. Primary MHC class II deficiency is a genetically heterogeneous disease of gene regulation that offers the unique opportunity of a genetic approach for the identification of the functionally relevant regulatory genes and factors. Most patients exhibit a characteristic defect in the binding of...

BACKGROUND High density lipoproteins (HDL) are complex lipoprotein particles involved in reverse cholesterol (C) transport and are negatively associated with the risk for coronary artery disease (CAD). We have described a disorder of familial HDL deficiency (FHD) due to abnormal cellular cholesterol efflux. In the present study, we investigated cellular cholesterol efflux on skin fibroblast fro...