We read with interest a recent paper by Pan et al on the relationship between the infrapatellar fat pad (IPFP) and knee osteoarthritis (OA). With an average follow-up of 2.6 years, the authors found that IPFP maximal area at baseline was negatively associated with changes in knee pain, but positively associated with change in tibial cartilage volume per annum, and reduced risks of increases in ...