v As we celebrate during the approaching holidays with loved ones and friends, we have much to be thankful for. The year 2004 has been outstanding for SIM and for MISQE. Our partnership has flourished, one example being the SIM white paper winners, which represent successful practitioner projects. In this edition of MISQE you will find the first place finisher, a paper titled " Innovation throu...

Recently we isolated a homolog of the Drosophila single-minded (sim) gene from a zebrafish cDNA library. The 4380-bp of zebrafish sim cDNA encodes a polypeptide of 585 amino acids with strikingly conserved bHLH and PAS A/B domains in the amino-terminal region. During embryogenesis, sim mRNA appears in the animal hemisphere as early as 3 h post-fertilization and is expressed in a widespread patt...

Background. Severe malaria is prevalent globally, yet it is an uncommon disease posing a challenge to education in nonendemic countries. High-fidelity simulation (sim) may be well suited to teaching its management. Objective. To develop and evaluate a teaching tool for severe malaria, using sim. Methods. A severe malaria sim scenario was developed based on 5 learning objectives. Sim sessions, c...

An overly aggressive immune response to the intestinal microflora in a genetically susceptible host background has been implicated in the pathogenesis of inflammatory bowel diseases. We measured the impact of a probiotic preparation (SIM) containing inulin on the severity of colitis and on intestinal microflora profiles of HLA-B27-beta(2)-microglobulin transgenic (TG) rats. SIM is a mixture of ...

HPAM Sim is an execution-driven simulator of heterogeneous machines. HPAM Sim allows the simulation of target machines consisting of different processors and interconnection networks. HPAM Sim attempts to reduce simulation time by using lightweight threads and static augmentation. Additionally, simulation can be performed either in contention or non contention mode. The results of HPAM Sim simu...

This file complains supplementary material, consisting of a proof and the details of an algorithm, to accompany a paper that appears in the proceedings of AAMAS 2010. The main paper is available at http://www.cs.utexas.edu/~pstone/ Papers/bib2html/b2hd-AAMAS2010-adhoc.html 3. PROOF OF THEORM 3.1 Theorem 3.1. It is never optimal for the teacher to pull Arm2. Proof. By induction on the number of ...

The Space Interferometry Mission (SIM) will be 10-m Michelson interferometer in Earth-trailing solar orbit. AS a part of NASA's Origins program, it will be the first space-based optical interferometer designed for precision astrometry. As well as enabling forefront astronomical science, SIM will serve as a technology pathfinder for future Origins missions, such as the Terrestrial Planet Finder ...

Photobleaching is a major factor limiting the observation time in fluorescence microscopy. We achieve photobleaching reduction in structured illumination microscopy (SIM) by locally adjusting the illumination intensities according to the sample. Adaptive SIM is enabled by a digital micro-mirror device (DMD), which provides a projection of the grayscale illumination patterns. We demonstrate a re...