The family of epidermal growth factor (EGF, EGFR, c-erbB-2) plays a pivotal role in gastric cancer progression, invasion and metastasizing. Helicobacter pylori infection is known to contribute significantly to the formation and progression of gastric cancer. However, the mechanisms responsible for this process have not been yet elucidated. We analysed the relationship between H. pylori infectio...

A 42-year-old man attended our outpatient department with melena for 1.5 years and vague epigastric pain for 2 days. He had a history of splenectomy because of trauma 17 years ago. Physical examination did not reveal any abdominal mass or enlargement of Virchow’s lymph nodes. A rectal digital examination and blood tests were also unremarkable. Gastroscopy revealed a submucosal mass with a super...

A 63-year-old woman was referred to our hospital to undergo endoscopic therapy for a lesion suspected of being early gastric cancer. A biopsy had already been performed. The diagnosis was adenoma with Helicobacter pylori, but cancer could not be ruled out. Esophagogastroduodenoscopic observations revealed a whitish, elevated lesion 20 mm in diameter with 4 large lobules and a central depression...

PURPOSE Laparoscopic wedge resection of gastric submucosal tumor may be difficult in case of the endophytic mass or the mass located unreachable area such as cardia, and intragastric approach can be useful. We would present the experiences of the intragastric wedge resection. MATERIALS AND METHODS There were 7 patients diagnosed as gastric submucosal tumor and underwent the intragastric wedge...

Amongst the varied, diverse causes of intraabdominal masses in infancy and early childhood, gastric teratomas (GTs) account for a very small proportion. A worldwide literature search reveals only around one hundred cases of GT and also supports the fact that its preoperative diagnosis remains elusive. Here we report the case of a two-month-old male who presented to the pediatric surgery outpati...

Gastric adenocarcinoma is a rare entity in the pediatric population. Gastric hepatoid adenocarcinoma with elevated serum alpha-fetoprotein (AFP) is seen extremely rarely in children. A 12-year-old boy was admitted to the hospital with complaint of abdominal pain. X-ray revealed free air density below the diaphragm. Emergent laparotomy showed perforated stomach. Four weeks after the operation, h...

Schwannomas are generally benign, slow growing tumors. They are rarely observed in the gastrointestinal tract with the most common site being the stomach. These tumors are usually asymptomatic. The preoperative diagnosis via endoscopy is a challenging issue due to the difficulty of differentiation from other submucosal tumors. A 54-year-old woman presented with epigastric pain persisting for th...

The rare phenomenon of tumor-to-tumor metastasis was first described in 1930. The donor neoplasm is most frequently lung or breast carcinoma, whereas intracranial meningiomas are reportedly the commonest recipient neoplasm. Here we report a case of metastasis from a primary gastric cancer to a uterine lipoleiomyoma. A 65-year-old woman presented with locally advanced gastric cancer with compute...