BACKGROUND Tramadol is a centrally acting analgesic that is often used in conjunction with nonsteroidal anti-inflammatory drugs (NSAIDs). The effect of coadministration of tramadol and indomethacin on gastric barrier function in dogs is unknown. HYPOTHESIS/OBJECTIVES That coadministration of a nonselective NSAID (indomethacin) and tramadol would decrease recovery of barrier function as compar...

BACKGROUND Terlipressin is a synthetic vasopressin analogue that is used in the treatment of bleeding esophageal varices and hepatorenal syndrome in patients with cirrhosis. Serious ischemic adverse events, such as skin necrosis involving the extremities, scrotum, trunk, and abdominal skin, are rarely observed. In the literature to date, 20 cases that developed ischemic skin necrosis due to ter...

HEADINGS – Gastric bypass. Gastroplasty. Bariatric surgery. Weight loss. ABSTRACT Background Use of ring in Roux-en-Y gastric bypass is still a matter of controversy among bariatric surgeons. There is no consensus on its impact in relation to weight loss and weight maintenance in the long term. Aim To evaluate the influence of the ring on the evolution of body weight over four years after baria...

We present a case of acute gastric band slippage with gastric necrosis and massive haemoperitoneum necessitating an emergency surgery. The patient presented with an 8h history of dysphagia, vomiting and epigastric pain. Initial examination was unremarkable, but within 6h the patient suddenly deteriorated with a distended peritonitic abdomen. At laparotomy the patient was found to have gastric b...

objective(s) the liver has major role in the organism homeostasis, interactions with other systems, synthesis and metabolism of bile production, drug detoxification and hormone inactivation. cholestasis can be defined as an impairment of the bile flow which can lead to hepatocytes necrosis and finally cirrhosis. some studies reported a gastric acid secretion reduction in cirrhotic subjects, whi...

Objective(s) The liver has major role in the organism homeostasis, interactions with other systems, synthesis and metabolism of bile production, drug detoxification and hormone inactivation. Cholestasis can be defined as an impairment of the bile flow which can lead to hepatocytes necrosis and finally cirrhosis. Some studies reported a gastric acid secretion reduction in cirrhotic subjects, wh...

UNLABELLED Recent studies have shown that stimulation of cannabinoid 1 (CB1) receptor reduces the area of ischemic myocardial necrosis and affects activity of the digestive tract. The aim of the present study was to check whether the administration of CB1 receptor agonist or antagonist affects the stress-induced gastric ulceration and development of edematous pancreatitis. METHODS Experiments...