Accidental methyl chloride poisoning caused by gas leakage from a refrigerator through a ruptured rubber connecting tube occurred in four members of a family. All the patients had symptoms of central nervous system and kidney damage, while in three of them jaundice was observed. The outcome of the intoxication was good in all cases. Methyl chloride poisoning was first described by Gerbis in 191...

Hydrogen sulfide is a highly toxic gas-second only to carbon monoxide as a cause of inhalational deaths. Its mechanism of toxicity is only partially known, and no specific therapy exists for sulfide poisoning. We show in several cell types, including human inducible pluripotent stem cell (hiPSC)-derived neurons, that sulfide inhibited complex IV of the mitochondrial respiratory chain and induce...

A mass outbreak of poisoning occurred in central Taiwan in 1979 due to the ingestion of rice-bran oil contaminated with polychlorinated biphenyls (PCBs), dibenzofurans (PCDFs) and quaterphenyls (PCQs). The incident was called PCB poisoning or Yu-Cheng in Taiwan. The major PCB and PCDF congeners in the toxic oil and in the blood and tissues of the poisoned patients were characterized by gas chro...

Purpose: The purpose of this study was to investigate the cause acute fatal poisoning and time death by analyzing National Emergency Department Information System (NEDIS) South Korea. Methods: NEDIS data from 2014 2018 excluding non-medical visits were used for study. patients with extracted using diagnostic codes. toxic substances classified into pharmaceuticals, pesticides, gases, artificial ...

Background: Analgesics are reported to be responsible for 11.3% of the poisoning events in the 20 y data obtained from the Poison Counseling Centers. In this study, we aimed to investigate the relationship between epidemiological characteristics of patients, drug levels detected in acetaminophen poisoning and course of the disease due to timely, late admission and severity of intoxication. Meth...

Trends in completed suicide by method were analysed for Belgium between 1968-1972 and 1978-1981, using the information reported on death certificates. Around 1980, hanging was the most preferred method of suicide in both sexes, followed by firearms in males and poisoning by solid and liquid substances in females. Between 1970 and 1980, rates for all but one method (domestic gas) increased. The ...

Paraquat is one of the most widely used herbicides in the world and is highly toxic to humans and animals. Respiratory failure as a result of lung injury is the most common cause of death from paraquat. In this study, we developed a lung metabolomic method by gas chromatography-mass spectrometry (GC-MS) to evaluate the effect of acute paraquat poisoning on rats. The acute paraquat poisoning gro...

The purpose of this review is to examine the literature regarding occult and chronic exposure to low levels of carbon monoxide (CO)— that is, levels insufficient to cause emergency department attendance or admission to hospital with a clinical diagnosis of acute CO poisoning, although this in fact is the cause of the symptoms. More is known about acute CO poisoning, but knowledge and awareness ...

BACKGROUND Carbon monoxide (CO) is an important source of poisoning in children. We performed this study in order to clarify the clinical characteristics of pediatric patients with CO poisoning. METHODS We identified and reviewed the medical records of pediatric patients diagnosed with CO intoxication and hospitalized in our department during a 10-year period. Epidemiologic and clinical data ...