THE MOST COMMONLY USED INDICATOR OF SLEEP DISORDERED BREATHING (SDB) SEVERITY IS THE RESPIRATORY DISTURBANCE INDEX (RDI), WHICH IS SYNONYMOUS WITH THE APNEA HYPOPNEA INDEX (AHI) IN MANY REPORTS. The RDI is the total number of apneas and hypopneas per hour of sleep. In clinical populations, the RDI is used to define the presence of SDB and thus identify individuals who require treatment.1,2 In a...

OBJECTIVE To examine links between obstructive sleep apnea (OSA), insulin resistance, and dyslipidemia. STUDY DESIGN Obese (body mass index [BMI] >95th percentile for age and gender) children who snored (n = 62, 46 males, age 10.89 [5-16 years] underwent polysomnography and metabolic studies. RESULTS Respiratory disturbance index (RDI) was 9.23 (0-95), with 23 children (39%) recommended for...

Berry, Susan A., Pearl L. Bergad, Allison M. Stolz, Howard C. Towle, and Sarah Jane Schwarzenberg. Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation: discordant responses to IL-6. Am. J. Physiol. 276 (Cell Physiol. 45): C1374–C1382, 1999.—The rat serine protease inhibitor (Spi) 2 gene family includes both positive (Spi 2.2) and negative (Spi 2.1) acute phase reactants,...

BACKGROUND The diagnosis of sleep-disordered breathing (SDB) and evaluation of sleep quality in the pediatric population is dependent on resource intensive attended polysomnography. An ECG-derived cardiopulmonary coupling sleep spectrogram (CPC) analysis previously described in adults can provide information about the severity of SDB and coupled interactions of sleep modulated autonomic drive a...

Relationship Development Intervention® (RDI®) is a cost effective, research guided, intervention approach for remediating Autism Spectrum Disorders (ASD). The purpose of RDI® is to develop intersubjectivity, the agreed upon core of autism’s social and communicative deficits (Baron-Cohen, 2000). Intersubjectivity encompasses joint attention, social referencing, theory of mind, social reciprocity...

BACKGROUND/AIM S-1 plus cisplatin is the standard first-line chemotherapy for metastatic gastric cancer (MGC) in Japan, but the relationship between dose intensity and antitumor effects remains unclear. PATIENTS AND METHODS We retrospectively studied 64 patients who received S-1 plus cisplatin for MGC from January 2006 to December 2010 in two Japanese hospitals. RESULTS The median relative ...

The demand for more functional plant-based proteins has greatly increased. objective of this study was to provide a systematic understanding the properties and physicochemical features protein isolates extracted from common pulses. Chickpea (ChPI) much less soluble compared other proteins. Pigeon pea (PiPI) lab soybean (SPI) possessed excellent emulsification capacity stability 0.71–0.73 0.70–0...

INTRODUCTION Obesity and male gender are the main risk factors for the development of obstructive sleep apnoea (OSA); however, some epidemiological data has shown that neck circumference (NC) > or = 43 cm is a better predictor of obstructive event frequency than body mass index (BMI). The aim of this study was to assess the relation between NC and BMI on OSA severity in males. MATERIAL AND ME...