the purpose of this study was to determine whether a 45 bp insertion/deletion (i/d) polymorphism in human uncoupling protein 2 (hucp2) gene was associated with changes in several cardiovascular risk and physical fitness factors in response to combined exercise during 12 weeks in korean middle-aged women. the changes in physiological parameters after combined exercise during 12 weeks were compar...

Urinary tract infections are one of the most common infectious diseases that lead to significant health problems in the world. Urinary tract infections are referred to any infection in any part of the renal system. Uropathogenic Escherichia coli, Proteus mirabilis, and Klebsiella are main organisms that are involved in these infections. After identifying same protective and conserved virulence ...

background: with the prevalence of 6-10%, polycystic ovarian syndrome (pcos) is considered the most common endocrinological disorder affecting women in their reproductive age. it has been suggested that genetic factors participate in the development of pcos. follicular development has been considered as one of the impaired processes in pcos. bone morphogenetic protein-15 (bmp-15) gene is a cand...

Gene–environment interactions have important implications for elucidating the genetic basis of complex diseases beyond joint function multiple factors and their (or epistasis). In past, G × E been mainly conducted within framework association studies. The high dimensionality interactions, due to complicated form environmental effects presence a large number including gene expressions SNPs, has ...

Perforin gene (PRF1) mutations have been reported in 20-30% of patients with familial hemophagocytic lymphohistiocytosis (FHL), an immune disorder of infancy and early childhood. Cytotoxic T and natural killer (NK) cell activities are remarkably reduced or ab-sent in FHL patients. We report the first cases of familial hemophagocytic lymphohistiocy-tosis in an Iranian family with two siblings. E...

Heterotrimenc G proteins participate in the signal transduction ens cade. Adult thyroid tumors have been shown to harbor specific point mutations in codons 201 and 227 of the G@asubunit of the adenylate cyclase stimulator. This protein affects the GDP/GTP turnover and finally results in an enhanced activation of G@and thus adenylate cyclase. We attempted to find out if G@agene mutations were pr...

A multi locus sequence analysis (MLSA approach) was studied on the Bacillus genus, or subtilis species complex for specific, including 08 strains from four (B. subtilis, B. pumilus, licheniformis and amyloliquefaciens) were provided by Biotechnology Center of Ho Chi Minh City. The research based sequences 16S rRNA genes, concatenation five protein-coding housekeeping genes: glpF, pta, purH, pyc...

Background: Human Adenovirus species D (HAdV-D) was common human viral pathogen especially in eye infection, consists of several types of which HAdV-D8, -D19 and –D37 were common in eye infection. This study includes detection of HAdV-D types implicated in conjunctivitis based on L2 (Penton protein) gene similarity. Methods: Conjunctival swabs were collected from Keratoconjunctivitis patient...