Research on olfaction has been fraught with considerable frustration because none of the hundreds of olfactory receptors make it to the cell surface on their own when expressed in heterologous systems. Recent work indicates that the heterodimerization of olfactory receptors with beta2-adrenergic receptors results in surface expression of these G protein-coupled receptors. Similar conclusions--t...

Heterotrimeric G proteins act as signal transducers that couple cell-surface receptors to cytoplasmic effector proteins. In fungi, G proteins play essential roles during sexual and pathogenic development. They are part of the pheromone signaling cascade in both ascomycetes and basidiomycetes, which is crucial for the recognition and fusion of cells of opposite mating type. In addition, G protei...

INTRODUCTION.....................................................................................512 I. GAGING THE RESPONSE TO HUMAN CLONING .................................517 A. Initial Reactions and Actions ........................................................517 B. Recent Attitudes Toward Human Cloning .....................................519 II. CAN A BAN ON HUMAN REPRODUCTIVE CLONING ...

We report the molecular cloning of two replication-competent osteoma-inducing murine leukemia viruses from the RFB osteoma virus stock (M. P. Finkel, C. A. Reilly, Jr., B. O. Biskis, and I. L. Greco, p. 353-366, in C. H. G. Price and F. G. M. Ross, ed., Bone--Certain Aspects of Neoplasia, 1973). Like the original RFB osteoma virus stock, viruses derived from the molecular RFB clones induced mul...

10.1016/S1674-6384(15)60054-5 Glycyrrhiza uralensis is frequently used in traditional Chinese medicine. This plant contains a large amount of effective constituents, including triterpenoids and flavonoids. Among them, glycyrrhizin is believed to be the marker compound to evaluate the quality of G. uralensis based on Chinese Pharmacopoeia. Many studies showed that glycyrrhizin possesses various ...

background: with respect to the prevalence of leishmaniosis in our country and the problems occurred in the therapeutic approaches and also with respect to the previous successful reports of paromomycin efficacy in this regard, the present study was conducted to determine the effects of paromomycin and gentamicine sulphate on promastigotes of leishmania major.materials and methods: it was an ex...