Invasive aspergillosis (IA) is a life-threatening infection. IA is usually seen in severely immunocompromised patients. However, IA as a presenting feature of non-Hodgkin's lymphoma is rare. The patient we describe had no signs or symptoms of lymphoma prior to hospital admission. A. fumigatus was isolated from respiratory tract specimens on the day of admission and fungal elements were detected...

Introduction. Candida is the cause of most systemic fungal infections that plays a role in pathophysiology sepsis newborns, especially premature infants with late-onset sepsis. The score can be used to assess occurrence candidosis where 2.5 accurately identify patients who are at high risk for candidiasis infection. Monocytes also play an important preventing candida invasion. Materials and met...

Haemophagocyticy lymyphohistiocytosis in the new-born is uncommon. Incidence reported between 1 50,000 to 1,50,000 admissions. Usually it primary or familial HLH first year of life. Secondary causes are due viral, bacterial and fungal infections. A dysmorphic small for gestational age male neonate presented with sepsis neonatal cholestasis. He also had associated HLH. Exom sequencing showed a 2...

BACKGROUND The incidence of fungal healthcare-associated infection (HAI) has increased in a major teaching hospital in the northern part of Taiwan over the past decade, especially in the intensive care units (ICUs). The purpose of this study was to determine the factors that were responsible for the outbreak and trend in the ICU. METHODS Surveillance fungal cultures were obtained from "steril...

Zygomycosis is a rare invasive opportunistic fungal infection that occurs in the setting of hematologic malignancies, chemotherapy-induced neutropenia, and immunosuppressive therapies. We report the first case of disseminated appendiceal zygomycosis due to Absidia spp. in a neutropenic patient who initially presented as acute appendicitis. A 63-year-old woman with acute myeloid leukemia present...

Simultaneous infections with multiple fungi may be misinterpreted as monomicrobial infections by current diagnostics with ramifications for the choice of antimicrobial agents that may impact patient outcomes. The application of molecular methods on tissue samples may be useful to decipher the aetiology of mixed fungal infections. We present a leukaemic patient who died from sepsis due to candid...

Host protection from fungal infection is thought to ensue in part from the activity of Syk-coupled C-type lectin receptors and MyD88-coupled toll-like receptors in myeloid cells, including neutrophils, macrophages and dendritic cells (DCs). Given the multitude of cell types and receptors involved, elimination of a single pathway for fungal recognition in a cell type such as DCs, primarily known...

BACKGROUND Dengue is a common cause of infection in adults in tropical countries. Sepsis is a syndrome of systemic manifestations induced by infection of any organisms; including bacterial, fungal and viral agents. Here, we investigated the diagnosis, management and outcomes of dengue patients presenting with sepsis in a prospective study of community-acquired sepsis in Thailand. METHODS From...

Blastoschizomyces capitatus is an emerging fungal pathogen. We describe a case of fungal sinusitis and invasive fungal septicemia due to B. capitatus in a 65-year-old male patient who was a known cardiac and diabetic patient. The patient was treated with antibiotics but succumbed due to delay in treatment with amphotericin-B. J Microbiol Infect Dis 2012; 2(4): 165-167