Introduction Since the late 1950s, health care visionaries have predicted an information technology (IT) revolution within medical care delivery—a revolution that would transform the health care industry as it had the finance and retail sectors. The early pioneers of medical informatics— the study and use of computers and IT in health care—formulated a vision for literally transforming modern m...

This paper explores the role played by government guarantees to banks’ foreign creditors as a root cause of self-fulfilling twin banking-currency crises. We develop a general equilibrium model in which such guarantees lead to these types of crises. Absent government guarantees, such crises are not possible. The model has three key properties. First, in the presence of government guarantees bank...

This document contains additional derivations that have been omitted in the main appendix, but which a reader might be interested in. In Section 1, I derive the expression for the change in the default threshold A∗ when the government implements the policy change with probability p ∈ (0, 1). In Section 2, I provide a detailed proof of Proposition B.1 reported in Section B.1 of the Appendix. In ...

Sovereign risk premia reflect investors’ beliefs for the equilibrium and off -equilibrium actions of international agents. This paper investigates the international dimension of self-fulfilling sovereign debt crises and characterizes self-interested bailouts (solidarity) and contagion. A credible bailout guarantee by a partner country or international agency can lower a debtor country’s borrowi...

Results A total of 155 patients with abnormal vital signs were identified, and nursing staff was interviewed about 139 patients. In 61 of these 139 patients, one or more vital signs were measured by the evening nursing staff. The respiratory rate was not measured by nursing staff. In 86 cases staff decided to intervene because of abnormal vital signs measured by study personnel. A total of 77% ...

The paper by Meyer-Lindenberg and colleagues in this issue of Neuron provides strong evidence that the absence of one or more genes in Williams syndrome leads to highly circumscribed pathology in the dorsal visual stream. This program of research demonstrates that neurocognitive architecture follows the same principles in typical and atypical development.

The activity of key metabolic enzymes is regulated by the ubiquitin ligases that control the function of the cyclins; therefore the activity of these ubiquitin ligases explains the coordination of cell-cycle progression with the supply of substrates necessary for cell duplication. APC/C (anaphase-promoting complex/cyclosome)-Cdh1, the ubiquitin ligase that controls G(1)- to S-phase transition b...

We develop a macroeconomic model with adverse selection. A continuum of households purchase goods from a continuum of anonymous producers. The quality of products can only be learned after trade. Adverse selection arises as low-quality goods deliver higher profits for producers but are less desirable for households. Higher aggregate demand induces more high-quality goods, raises average quality...