BACKGROUND & OBJECTIVES The aim of the present study is to investigate the physicochemical equivalence of seven brands of tablets containing chloroquine phosphate, an antimalarial purchased from different retail pharmacy outlets. METHODS The quality and physicochemical equivalence of seven different brands of chloroquine phosphate tablets were assessed. The assessment included the evaluation ...

The investment casting of reactive Ti and TiAl alloys requires the use of selected ceramics in the face-coat layer to prevent the reaction between the cast metal and ceramic shell, avoiding the formation of a hard layer at the metallic components surface. This work aims to study the influence of ceramic shells composition in some of its characteristics such as flexural strength, friability and ...

BACKGROUND Orally disintegrating tablets (ODTs) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. These tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. The aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mon...

Ondansetron hydrochloride is an intensely bitter antiemetic drug used to treat nausea and vomiting following chemotherapy. The purpose of the present work was to mask the taste of ondansetron hydrochloride and to formulate its patient-friendly dosage form. Complexation technique using indion 234 (polycyclic potassium with carboxylic functionality) and an ion-exchange resin was used to mask the ...

The usage of fixed dose combination (FDC) tablets of Lamivudine and Tenofovir Disoproxil Fumarate (TDF) is increasing due to increased incidences of HIV/Hepatitis B and HIV/TB co-infections. This is likely to increase the financial crisis due to limited resources for funding procurement of ready-made products from the pharmaceuticals manufacturing leading countries. Therefore, production of loc...

The objective of the present study was to prepare the fast disintegrating tablet of Salbutamol Sulphate, Cetirizine Hydrochloride in combined tablet dosage form for respiratory disorders such as bronchitis, asthma, and coughing for pediatrics and geriatrics. The tablets were prepared by direct compression technique. Superdisintegrant such as Sodium Starch Glycolate was optimized as 4% on the ba...

Article history: Received on: 09/07/2013 Revised on: 16/09/2013 Accepted on: 03/10/2013 Available online: 31/10/2013 The aim of the study was to develop a formulation of Ticagrelor 90 mg tablets that is equivalent to the reference product using similar excipients to match the in-vitro dissolution profile. A compressed coated tablet was formulated consisting of Ticagrelor and excipients conformi...

Abstract Purpose Gastroretentive drug delivery systems (GRDDS) have attracted interest for enhancement of absorption and bioavailability some drugs. Itopride hydrochloride (ITOP) is a used treatment gastroesophageal reflux other gastric motility disorders, but characterized by narrow window short in vivo half-life. Therefore, it expected that its formulation expanding gastroretentive tablets wo...

Thunbergia laurifolia Lindl. is a medicinal plant that belongs to the family of Acanthaceae. It possesses several biological and pharmacological activities. According Thai National List Essential Medicines, T. leaves are used for treatment fever. This work sought optimize microwave-assisted drying leaf granules shorten granule process by 32 full factorial design. Power was varied from 300, 450 ...