Mantle cell lymphoma (MCL)represents 5-10% of all B-cell non-Hodgkin lymphomas (NHL) and is characterized by the proliferation of mature B-lymphocytes, usually co expressing CD5, that infiltrate lymphoid tissues, bone marrow, peripheral blood, and extranodal sites [1]. Genetically, MCL is characterized by the t (11;14) (q13;32) translocation which leads to the rearrangement and over expression ...

We present a 10-year old boy with recurrent swelling of the right mandibular region. Based on the diagnosis of chronic recurrent parotitis, he received only supportive treatment. Because of frequent relapses, the diagnosis was reconsidered. Magnetic resonance imaging, scintigraphy and biopsy were compatible with chronic osteomyelitis. This lead to a diagnosis of mandibular primary chronic osteo...

Toxigenic Clostridium difficile is a frequent cause of infectious nosocomial diarrhea accounting for up to 25% of nosocomial diarrhea cases. Clinically significant disease is thought to be due almost exclusively to C. difficile strains that produce both toxin A and toxin B. Toxigenic C. difficile produces a broad spectrum of gastrointestinal disease varying from asymptomatic carriage to fulmina...

Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a non-bacterial inflammatory disorder of unknown cause occurring in children and adolescents. It is characterized by the insidious onset of pain and swelling to multifocal involved bones, recurring over months to years. Non-steroid anti-inflammatory drugs (NSAIDs) and steroids are the first choice for the initial and relapse treatment. Howeve...

The best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa (PAN). In human immunodeficiency virus (HIV)-related vasculitis this strategy is also effective and does not jeopardize, like cytotoxic a...

Behçet's disease (BD) is a chronic, relapsing, multisystem disorder, characterized by recurrent oral ulcer, genital ulcers, eye lesion, and skin lesion. The underlying pathology is nonspecific vasculitis of all vessel sizes, and severe vasculitis can result in fistula formation of neighboring tissues due to a necrotic process. Herein, eleven cases of BD combined with fistula are presented. In t...

Prostate cancer represents the most frequent non-cutaneous neoplasia in males. This type of neoplasia can develop peculiar patterns of evolution, presenting, in many cases, precocious relapses and metastasis. Bone metastasis in the mouth is extremely rare, and represents 1% of all malignant mouth neoplasias. The aim of the present study is to report a clinical case of bone metastasis in the man...

INTRODUCTION Chronic relapsing conditions are the most frustrating problems in day-to-day practice. In dermatological practice there are many such types of conditions which are resistant to routine therapeutic measures. Sometimes these measures may give rise to short-term remission but relapses are quite frequent. Quite often the modern drugs and antibiotics have a deleterious effect on the ski...