Historians have unanimously credited Christopher Wren with having constructed a weather clock (a self-registering instrument) in the early 1660s. This conclusion was based on account of French diplomat Balthasar de Monconys, which included sketch uncannily similar to an undated drawing by clock. By critically re-examining available sources, I argue that one can infer never actually What Moncony...

Software architectural knowledge (AK) is the integrated representation of the software architecture (SA) of a software-intensive system, the architectural design decisions, and the external context/environment. AK annotation using AK conceptual model is used to recover formal AK from SA documentation, including architecture design as well as the design decisions, rationale, context, and other f...

Integrins are cell surface receptors that bind cells to their physical external environment, linking the extracellular matrix to cell function. They are essential in the biology of all animals. In the late 1980s, we discovered that integrins are required for the ability of breast epithelia to do what they are programmed to do, which is to differentiate and make milk. Since then, integrins have ...