During the Middle Ages, the partition of the cadaver of the elite members was a current practice, with highly technical treatment given to symbolic organs such as the heart. Considered mostly from a theoretical point of view, this notion of dilaceratio corporis has never been biologically explored. To assess the exact kind of embalming reserved to the heart, we performed a full biomedical analy...

UNLABELLED PREMISE OF THE STUDY Novel nuclear exon-primed intron-crossing (EPIC) markers were developed to increase phylogenetic resolution among recently diverged lineages in the frankincense and myrrh family, Burseraceae, using Citrus, Arabidopsis, and Oryza genome resources. • METHODS AND RESULTS Primer pairs for 48 nuclear introns were developed using the genome resource IntrEST and we...

Frankincense is an aromatic terpenoid oleo-gum resin produced by trees in the genus Boswellia. It has been used for medicinal and religious purposes millennia, today important component perfume aromatherapy. The of Boswellia frereana especially prized, found to contain a high proportion monoterpenes. However, previous studies have relied on commercial samples; this study, we characterize compos...

One of the leading causes of death worldwide is cardiovascular disease, hence searching for a cure is an important endeavor. The totally safe, edible, and inexpensive Boswellia plant exudate, known as olibanum or frankincense, is considered to possess diverse medicinal values in traditional medicine and from recent biological studies. Investigating the cardioprotective and antioxidant activitie...

Frankincense and myrrh are highly effective in treatment of inflammatory diseases, but lacking of thetherapy mechanisms. We undertook this study to evaluate the effects on Adjuvant-induced Arthritis(AIA) rats and to explore the underlying mechanisms by analyzing the metabolic profiling and signalingpathway evaluated by expression of inflammatory cytokines, c-jun and c-fos and corresponding phos...

Boswellia serrata gum resin –a.k.a. frankincense – has traditionally been used as an anti-inflammatory agent in Ayurvedic medicine. More recently, extracts of this resin enriched in boswellic acids have demonstrated anti-inflammatory properties in rodents and beneficial clinical effects in arthritis, colitis, and brain edema, without notable side effects. Although initial reports suggested that...

Herbs and hand-made herbal remedies have been long used for disease control, treatment, health improvement. Evidence suggests that a single herb’s compounds can synergistic functions with probably no adverse effect. Unfortunately, the traditional administration of essential oil (EO) does not follow regulatory dose regimen, causing reduced bioavailability due to EO evaporation or denaturation in...