The aminomethylation of hydroxylated isoflavones with 2-aminoethanol, 3-amino-1-propanol, 4-amino-1-butanol, and 5-amino-1-pentanol in the presence of excess formaldehyde led principally to 9-(2-hydroalkyl)-9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]-oxazin-4-ones 4 and/or the tautomeric 7-hydroxy-8-(1,3-oxazepan-3-ylmethyl)-4H-chromen-4-ones 5. The ratio of these tautomers was dependent on solvent...

The NmlR(sp) transcription factor of Streptococcus pneumoniae is shown to induce adhC (alcohol dehydrogenase) expression in the presence of both formaldehyde and methylglyoxal. nmlR(sp) and adhC mutant strains display altered and opposite aerobic growth phenotypes. The nmlR(sp) strain exhibits increased resistance to high oxygen tension, attributable to decreased H(2)O(2) production, which corr...

BACKGROUND Positive patch test reactions to formaldehyde-releasers in patients co-reacting to formaldehyde are often ascribed to formaldehyde allergy. However, the formaldehyde content of patch test materials has not been investigated. OBJECTIVES To demonstrate and quantify free formaldehyde in commercial patch test materials and in prepared aqueous solutions of formaldehyde releasers. MATE...

HeLa cells were exposed to formaldehyde and its metabolic derivatives, methanol, formic acid, and acetaldehyde, to investigate that the toxicity of formaldehyde is not caused by the chemical group. After 1 h of treatment with formaldehyde, mitochondrial assays showed that low concentrations (e.g. 10 μmol/L) of formaldehyde promoted growth of the HeLa cells, while higher concentrations (e.g. ≥62...

background: formaldehyde is one of the most serious air contaminant that can be found everywhere. some of the source of formaldehyde include product of building materials, decorated materials, cigarette smoke, etc. aldehydes compounds especially formaldehyde are used as disinfectants for sterilization in different industries. in this study we measured formaldehyde workplace exposure with niosh ...

conclusions according to the results of this study, vitamin e probably improves the harmful effects of formaldehyde on rat kidney tissue. results comparison of the control and formaldehyde groups with the vitamin e group revealed that there were significant differences in lumen size and nuclear color of proximal tubules in rats treated by vitamin e (p < 0.05). cell degeneration, lumen size, num...

Formaldehyde is a highly toxic chemical common in industrial effluents, and it is also an intermediate in bacterial metabolism of one-carbon growth substrates, although its role as a bacterial growth substrate per se has not been extensively reported. This study investigated two highly formaldehyde-resistant formaldehyde utilizers, strains BIP and ROS1; the former strain has been used for indus...