Incubation (30 degrees) of fat cell particulate fractions with fluoride before assay in the effective absence of fluoride results in activation of adenylate cyclase. Whereas the effect of fluoride (1.3 to 7 mM) when added to the assay was maximal in less than 2 min, 10 or 15 min of incubation before assay was usually required to produce maximal activation with any given concentration of fluorid...

The use of voriconazole, a trifluorinated antifungal, has been associated with the development of fluoride excess and periostitis/exostoses. We evaluated a cohort of patients on long-term triazole therapy and found that other fluorinated triazoles (fluconazole and posaconazole) conferred no risk for the development of hyperfluorosis and its complications in our cohort.

OBJECTIVE To determine fluoride excretion under various conditions of fluoride intake and to estimate the fractional urinary excretion of fluoride in individual children participating in a school milk fluoridation scheme. DESIGN In the first part of the study, individual urine samples were collected from each of eight 4 to 5-year-old children for a continuous period of 55 h. For each child (n...

The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding ...

Background; Fluoride is an essential nutrient for the human body. The major routes of fluoride intake include food and drinking water, though the absorption of fluoride from food is much easier. The aim of this study was to evaluate the amount of fluoride in the soil and tomato and onion crops on farms of Zanjan. Methods; Three farms of each crop (tomato and onion) were selected randomly. Ea...

Introduction Fluoride (F−) is an important anion, present in various environmental, clinical and food samples. Small amounts of fluoride are vital for the human organism, but it is toxic in larger amounts. For adults the lethal dose is 0.20–0.35 g F− per kg body weight. Fluoride is widely used in various branches of industry and some fluoride compounds are formed as by-products in certain proce...

Crop field soil collected from Sambalpur University campus of Odisha and treated with various fluoride concentrations was used to raise selected local crops. Background concentration of total and leachable fluoride content in soil was 95.19 and 8.89 ppm respectively. At the time of harvest of the crops, the total fluoride content was found to decrease and leachable fluoride content was found to...

prolonged excessive intake of fluoride during child's growth and development stages has been associated with mental and physical problems. the aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (iq) of children living in five rural areas in makoo/iran.in this cross-sectional study, 293 children aged 6-11 years were selected from five villag...