Two cases are presented which exhibit classical dental fluorosis in the permanent dentition which is most logically explained by the excessive intake of fluoride. The cases emphasize the narrow therapeutic range of systemic fluorides in children and the need for analyzing samples of local drinking water before caries-preventive fluoride therapy can be initiated. The potential for induction of f...

The actual mechanism of fluoride action is still a subject of debate. A dogma has existed for many decades, that fluoride has to be ingested and acts mainly pre-eruptively. However, recent studies concerning the systemic effect of fluoride supplementation concluded that the caries-preventive effect of fluoride is almost exclusively posteruptive. Moreover, epidemiologists have cast doubt on the ...

The ATPases of isolated membranes of lactic acid bacteria were found to be inhibited by fluoride in a complex manner. Among the enzymes tested, that of Streptococcus mutans GS-5 was the most sensitive to fluoride, and the initial rate of hydrolysis of ATP was reduced 50% by approximately 3 mM fluoride. The enzyme of Lactobacillus casei ATCC 4646 was the most resistant, and about 25 mM fluoride ...

The decline of dental caries in the industrialized countries can be attributed to widespread use of fluorides. The Japanese market share of dentifrices containing fluorides has increased from 12% in 1985 to 77% in 2000. For a fluoride dentifrice to be effective in the control of dental caries, an adequate concentration of the fluoride must be soluble. Several Japanese fluoride dentifrices have ...

Fluoride is recognized as an effective agent for dental caries prevention. Generally, the main source of fluoride intake is drinking water. In this study, fluoride content in 18 commercial brands of bottled waters was investigated. Six samples from each batch of 18 Iranian commercial brands of bottled waters were supplied. The fluoride content of samples was analyzed by Fluoride Ion Selective E...

Suckling rat pups were given intraperitoneal fluoride injections at selected ages so that we could study fluoride uptake in the enamel of the maxillary first molar at various stages of enamel development. Plasma fluoride levels in six-day-old and 11-day-old pups were monitored following the intraperitoneal injection of fluoride. The findings indicate that: (1) fluoride was more easily taken up ...

This report describes the benefits to dental health of exposure to fluorides and the toxicologic effects of fluorides based on the relevant scientific literature published through September 1988. In general, original reports were used for evaluation of results between 1980 and 1988, and review articles were used for results published prior to 1980. This report is confined to effects of inorgani...

BACKGROUND The knowledge of background alimentary fluoride intake in preschool children is of utmost importance for introducing optimal and safe caries preventive measures for both individuals and communities. The aim of this study was to assess the daily fluoride intake analyzing duplicate samples of food and beverages. An attempt was made to calculate the daily intake of fluoride from food an...

background existence of fluoride in drinking water above the permissible level causes human skeletal fluorosis. objectives electrocoagulation by iron and aluminum electrodes was proposed for removing fluoride from drinking water. materials and methods effects of different operating conditions such as treatment time, initial ph, applied voltage, type and number of electrodes, the spaces between ...