Protein kinases and their substrates comprise extensive signaling networks that regulate many diverse cellular functions. However, methods and techniques to systematically identify kinases directly responsible for specific phosphorylation events have remained elusive. Here we describe a novel proteomic strategy termed fluorescence complementation mass spectrometry (FCMS) to identify kinase-subs...

In this work, tungsten coil (W-Coil) devices are used as atomizers for electrothermal atomization atomic absorption spectrometry (ETAAS), electrothermal atomization laser excited atomic fluorescence spectrometry (ETA-LEAFS), and electrothermal vaporization inductively coupled plasma atomic emission spectrometry (ETV-ICP-AES). For most cases in ETAAS and ETA-LEAFS, limits of detection (LODs) usi...

The purpose of detecting trace concentrations of analytes often is hindered by occurring noise in the signal curves of analytical methods. This is also a problem when different arsenic species (organic arsenic species such as arsanilic acid, nitarsone and roxarsone) are to be determined in animal meat by HPLC-UV-HG-AFS, which is the basis of this work. In order to improve the detection power, m...

Several commercial soft drinks and respective plastic bottles were analyzed for their multielement contents employing the synchrotron radiation total reflection X-ray fluorescence spectrometry technique (SRTXRF). The SRTXRF method has been developed and validated, and about 20 elements were detected in the investigated samples, including some trace elements, which can be toxic for human beings,...

Inductively coupled plasmas (ICP) offer promise as atomization cells for atomic fluorescence spectrometry (AFS). In this study, an ICP formed part of a modular spectroscopic system for atomic fluorescence, emission, and absorption measurements. Details on the assembly of the complete system are provided. Mlcrowave-excited, thermostated, electrodeless dlscharge lamps were used as prlmary sources...

A multivariate data analysis procedure that uses singular value decomposition and the Ho-Kashyap algorithm is proposed to obtain calibration constants for x-ray fluorescence spectrometry. These calibration constants can be used to obtain results from experimental data by means of a simple dot product calculation. The method was tested on experimental data from the literature. Comparison of resu...

Abstract L‐ascorbic acid (AA) is an essential nutrient that plays a vital role in our day‐to‐day body function, and maintaining health, for example, by serving as antioxidant. AA oxidation generates various products, some of which have not been identified. In this investigation, we show the room temperature reaction with copper sulfate (CuSO 4 ) product exhibits blue fluorescence. We studied ho...

Donor molecules of the D-π-A-π-D type structure are often used for applications in organic photovoltaics. In this communication, bromination 4,7-di(thiophen-2-yl)-[1,2,5]thiadiazolo[3,4-d]pyridazine followed by Suzuki cross-coupling with carbazoleboronic acid gave 4,7-bis( 5-(9-hexyl-9H-carbazol-3-yl)thiophen-2-yl)-[1,2,5]thiadiazolo[3,4-d]pyridazine. The newly synthesized compounds was establi...

Sodium in the coals of West China has received persistent attention due to its high contents and severe pollutions’ problems during coal utilization. A total seven drill samples Jurassic from Tatuo coalfield, Qinghai Province, were collected analysed using optical microscopy, scanning electron microscopy conjunction with energy-dispersive X-ray spectrometry, powder diffraction, inductively coup...

This paper reviews the current research on the speciation and determination of mercury by various analytical techniques, including the atomic absorption spectrometry (AAS), voltammetry, inductively coupled plasma optical emission spectrometry (ICP-OES), ICP-mass spectrometry (MS), atomic fluorescence spectrometry (AFS), spectrophotometry, spectrofluorometry, and high performance liquid chromato...