Activation of receptor tyrosine kinases triggers many developmental decisions, yet we do not understand how activation of a single receptor can be transduced into different cell responses. The torso pathway in Drosophila provides a model to address this issue since it generates more than one response in the embryo. The torso receptor tyrosine kinase is activated at the embryonic poles under the...

BACKGROUND The role of routine dedicated spinal imaging and immobilisation following gunshot wounds (GSW) to the head, neck or torso has been debated. The purpose of this study was to determine the incidence of spinal column injury requiring stabilisation in evaluable patients following gunshot injury. METHODS A retrospective study from of a Level I trauma centre from January 1995 to December...

There is a need for a hand-heating system that will keep the hands warm during cold exposure without hampering finger dexterity. The purpose of this study was to examine the effects of torso heating on the vasodilative responses and comfort levels of cooled extremities during a 3-h exposure to -15 degreesC air. Subjects were insulated, but their upper extremities were left exposed to the cold a...

The aim of the present paper is to evaluate the influence of the Soil- Foundation- Structure Interaction (SFSI) effects on the component demand modifier factor of concrete gravity beams based on ASCE 41-06 standard. To this end, the beam on the nonlinear Winkler foundation approach is employed which is a simple and efficient method. At first, four sets of 3-, 6-, 10- and 15-storey concrete mome...

Understanding smart grid cyber attacks is key for developing appropriate protection and recovery measures. Advanced attacks pursue maximized impact at minimized costs and detectability. This paper conducts risk analysis of combined data integrity and availability attacks against the power system state estimation. We compare the combined attacks with pure integrity attacks false data injection (...

BACKGROUND We sought to determine torso injury rates and sensitivities associated with fluid-positive abdominal ultrasound, metabolic acidosis (increased base deficit and lactate), and impaired pulmonary physiology (decreased spirometric volume and PaO2/FiO2). METHODS Level I trauma center prospective pilot and post-pilot study (2000-2001) of stable patients. Increased base deficit was < 0.0 ...

in this paper, the flexible job shop scheduling problem with machine flexibility and controllable process times is studied. the main idea is that the processing times of operations may be controlled by consumptions of additional resources. the purpose of this paper to find the best trade-off between processing cost and delay cost in order to minimize the total costs. the proposed model, flexibl...

When a transmembrane receptor protein tyrosine kinase (RTK) is expressed throughout the plasma membrane, yet only a specific handful of them must be activated, what's a ligand to do? During the development of the anterior and posterior termini of the Drosophila embryo, uniformly secreted ligand precursors are activated by proteolysis near the location of the receptors that must be activated. St...