نتایج جستجو برای: fission

تعداد نتایج: 14853  

2010
Jincheng Li Stefan Donath Yanrui Li Danian Qin Bellur S. Prabhakar Peifeng Li

miRNAs participate in the regulation of apoptosis. However, it remains largely unknown as to how miRNAs are integrated into the apoptotic program. Mitochondrial fission is involved in the initiation of apoptosis. It is not yet clear whether miRNAs are able to regulate mitochondrial fission. Here we report that miR-30 family members are able to regulate apoptosis by targeting the mitochondrial f...

2018
Jia Qi Feng Wang Ping Yang Xuelian Wang Renjie Xu Jihui Chen Yanggang Yuan Zhaoyang Lu Junli Duan

Hypertension-induced cardiac apoptosis is a major contributor to early-stage heart-failure. Our previous studies have found that p53-mediated mitochondrial fission is involved in aldosterone-induced podocyte apoptosis. However, it is not clear that whether p53-induced mitochondrial fission is critical for hypertensive Angiotensin II (AngII)-induced cardiomyocyte apoptosis. In this study, we fou...

Journal: :The Plant cell 2010
Xinchun Zhang Jianping Hu

Peroxisomes are highly dynamic organelles involved in various metabolic pathways. The division of peroxisomes is regulated by factors such as the PEROXIN11 (PEX11) proteins that promote peroxisome elongation and the dynamin-related proteins (DRPs) and FISSION1 (FIS1) proteins that function together to mediate organelle fission. In Arabidopsis thaliana, DRP3A/DRP3B and FIS1A (BIGYIN)/FIS1B are t...

Journal: :Physical Review C 2021

Neutron star merger ejecta are currently the most viable astrophysical site for $r$-process nucleosynthesis. Fission plays a fundamental role. The manuscript presents an updated scission-point model fission fragment distributions, which improves agreement with experimental yields. Two scenarios, based on alternative weak-interaction hypotheses, employed to reanalyze role of fission. Regions nuc...

2017
Jing Jin Xin Shen Yu Tai Shanliang Li Mingyu Liu Changlin Zhen Xiuchen Xuan Xiyue Zhang Nan Hu Xinzi Zhang Deli Dong

Mitochondria are morphologically dynamic organelles which undergo fission and fusion processes. Our previous study found that arterial constriction was always accompanied by increased mitochondrial fission in smooth muscle cells, whereas inhibition of mitochondrial fission in smooth muscle cells was associated with arterial relaxation. Here, we used the typical vasorelaxants, verapamil and phen...

2005
B. Jurado C. Schmitt K.-H. Schmidt J. Benlliure A. R. Junghans

The conditions for the manifestation of transient effects in fission are carefully examined by analysing experimental data where fission is induced by peripheral heavy-ion collisions at relativistic energies. Experimental total nuclear fission cross sections of U at 1⋅A GeV on gold and uranium targets are compared with the predictions of a nuclear-reaction code, where transient effects in fissi...

2005
JONATHAN B. GELLER LAURIE J. FITZGERALD CHAD E. KING

SYNOPSIS. Sea anemones (Phylum Cnidaria; Class Anthozoa, Order Actiniaria) exhibit a diversity of developmental patterns that include cloning by fission. Because natural histories of clonal and aclonal sea anemones are quite different, the gain and loss of fission is an important feature of actiniarian lineages. We have used mitochondrial DNA and nuclear intron DNA phylogenies to investigate th...

2014
Laura M. Westrate Jeffrey A. Drocco Katie R. Martin William S. Hlavacek Jeffrey P. MacKeigan

Mitochondria are dynamic organelles that undergo constant remodeling through the regulation of two opposing processes, mitochondrial fission and fusion. Although several key regulators and physiological stimuli have been identified to control mitochondrial fission and fusion, the role of mitochondrial morphology in the two processes remains to be determined. To address this knowledge gap, we in...

Journal: :Genes & development 2013
Thierry Doan Jeff Coleman Kathleen A Marquis Alex J Meeske Briana M Burton Erdem Karatekin David Z Rudner

How bacteria catalyze membrane fission during growth and differentiation is an outstanding question in prokaryotic cell biology. Here, we describe a protein (FisB, for fission protein B) that mediates membrane fission during the morphological process of spore formation in Bacillus subtilis. Sporulating cells divide asymmetrically, generating a large mother cell and smaller forespore. After divi...

Journal: :Current Biology 2005
Kurt J. De Vos Victoria J. Allan Andrew J. Grierson Michael P. Sheetz

Mitochondria display a variety of shapes, ranging from small and spherical or the classical tubular shape to extended networks. Shape transitions occur frequently and include fusion, fission, and branching. It was reported that some mitochondrial shape transitions are developmentally regulated, whereas others were linked to disease or apoptosis. However, if and how mitochondrial function contro...

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