نتایج جستجو برای: fisetin
تعداد نتایج: 382 فیلتر نتایج به سال:
Flavonoids, which are plant polyphenols, are now widely used in supplements and cosmetics. Here, we report that 4'-methylflavonoids are potent inducers of melanogenesis in B16F10 melanoma cells and in mice. We recently identified salt inducible kinase 2 (SIK2) as an inhibitor of melanogenesis via the suppression of the cAMP-response element binding protein (CREB)-specific coactivator 1 (TORC1)....
The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-d/l-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compound...
Abstract Background and Aims The prevalence of hyperuricemia is rising rapidly around the world, increasing evidence demonstrates that independent risk factor for chronic kidney diseases (CKD) development progression. Hyperuricemia-induced renal injury, namely hyperuricemic nephropathy (HN), characterized by urate crystal formation, tubulointerstitial fibrosis glomerulosclerosis, which would ev...
AMA Wang Y, Wu X, Ren W, et al. Protective effects of fisetin in an Aβ1-42-induced rat model Alzheimer’s disease. Folia Neuropathologica. 2023. doi:10.5114/fn.2023.126893. APA Wang, Y., Wu, X., Ren, W., Liu, Dai, & S. (2023). https://doi.org/10.5114/fn.2023.126893 Chicago Yunting, Xueling Wujiang Yanxia Shuo and Qing Huo "Protective disease". Harvard S., Huo, Q., Sun, Y. MLA Yunting disease." N...
Background: Asthma is a very common, non-communicable, chronic respiratory disease, with high incidence rate worldwide. Currently, no permanent therapeutic strategies are available for the treatment of asthma. Drugs, such as corticosteroids, β2-agonists, and anticholinergics, only temporarily reduce symptoms have various adverse effects. In this study, we investigated use fisetin, readily natur...
The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quer...
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