INTRODUCTION Multiple factors, including proteinuria, antiphospholipid syndrome, thrombocytopenia and hypertension, are predictive of pregnancy loss in systemic lupus erythematosus (SLE). In the PROMISSE study of predictors of pregnancy loss, only a battery of lupus anticoagulant tests was predictive of a composite of adverse pregnancy outcomes. We examined the predictive value of one baseline ...

Background: Normal pregnancy is thought to be dependent on Th2 deviation, while Recurrent Pregnancy Loss (RPL) and Pre-eclampsia (PE) appear to be biased toward the Th1 immune response. It is believed that the soluble form of CD30 (sCD30) is an index of Th2 immune response or modulator of Th1/Th2 responses. Objective: The aim of this study was determination of the sCD30 level in RPL and PE pati...

Objective: This study was designed to test the null hypothesis that first trimester ultrasound crown-rump length measurement for gestational age determination will result in no difference in the rate of induction of labor for postterm pregnancy, compared with second trimester biometry alone. Study design: Two hundred eighteen women were randomly assigned to receive either first trimester ultras...

background: abnormal levels of the markers afp, hcg, and ue3 could be useful in predicting adverse pregnancy outcomes. this study was designed to determine the correlation between second trimester maternal serum markers and adverse pregnancy outcome (apo). methods: in this historical cohort study, we randomly followed 231 obstetric patients with quadruple screening test in 14-18 weeks of gestat...

BACKGROUND The aim of this study was to evaluate the interrelationships between maternal serum leptin level and body mass index (BMI) at different gestational ages or during the whole pregnancy. METHODS A total of 374 blood samples were obtained from 114 pregnant women when they visited the prenatal clinic for registration, Down syndrome screening test, 50 g oral glucose challenge test, hepat...

This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...

background: various studies have come to contradictory results regarding the relationship between maternal hemoglobin (hb) level and adverse pregnancy outcomes. the present study aimed to investigate the birth outcomes among pregnant women who had normal hemoglobin levels in the first trimester of their pregnancy. patients and methods: in this prospective study, 108 healthy pregnant women with ...

This study aimed to establish a method of screening for pregnancy hypertension by a combination of maternal variables, including mean arterial pressure, uterine artery pulsatility index, pregnancy-associated plasma protein-A, and placental growth factor in early pregnancy. The base-cohort population constituted of 7797 singleton pregnancies, including 34 case subjects who developed preeclampsia...

receiver operating characteristics (roc) curves have numerous applications for identifying a cut-off point in diagnostic tests. nonetheless, given that sometimes two cut-off points have to be specified simultaneously, the roc curve can be used to identify such points. the volume under the roc surface (vus) serves as a criterion for the accuracy of diagnostic tests. one of the unfortunate outcom...

BACKGROUND Physical activity (PA) patterns during pregnancy have not been explored in depth and most previous studies lack assessment of variables such as type, frequency, duration and intensity of activity. OBJECTIVES This study had two goals: 1) to analyze PA patterns during pregnancy according to weekly time spent on different types of activity; and 2) to determine women's perception about...