Two common metrics of particle pollution measure the total number of particles (particle number) and the total mass of the particles (particle mass). This work analyzes particle number and mass emission rates measured from the exhaust of a 2002 diesel transit bus in real-driving conditions using on on-board mini-dilution system. The number concentrations were measured using the Electrical Low P...

BACKGROUND Increased concentrations of particles in air have been related to changes in inflammatory markers that in turn are hypothesized in mediating the particle effects on cardiovascular disease. The present work examined this association in an elderly cohort in the Greater Boston area and addresses the relative role of particles from different sources. METHODS The study included 710 subj...

Considerable attention has been given to the health effects of ambient air borne particulate matter as the Environmental Protection Agency (EPA) revises the National Ambient Air Quality Standards (NAAQS). Much of the recent focus has been on the effects of fine particles, with the establishment of additional monitoring platforms to measure both fine and coarse particles for epidemiological stud...

While particulate matter (PM) in the atmosphere can lead to a wide array of negative health effects, the cause of toxicity is largely unknown. One aspect of PM that likely affects health is the chemical composition, in particular the transition metals within the particles. Chromium is one transition metal of interest due to its two major oxidation states, with Cr(III) being much less toxic comp...

Air pollution contributes to acute exacerbations of asthma and the development of asthma in children and adults. Airway epithelial cells interface innate and adaptive immune responses, and have been proposed to regulate much of the response to pollutants. Thymic stromal lymphopoietin (TSLP) is a pivotal cytokine linking innate and Th2 adaptive immune disorders, and is upregulated by environment...

The aim of the investigation was to assess the relations between pairs of personal, indoor, and outdoor levels of fine particles and their components with respect to effects for older subjects with cardiovascular disease. In the framework of a study funded by the European Union (Exposure and Risk Assessment for Fine and Ultrafine Particles in Ambient Air; referred to as ULTRA)*, panel studies w...

Daily average monitoring data for PM10, PM2.5 and PM1.0 and meteorological parameters at Chengdu from 2009 to 2011 are analyzed using statistical methods to replicate the effect of urban air pollution in Chengdu metropolitan region of the Sichuan Basin. The temporal distribution of, and correlation between, PM10, PM2.5 and PM1.0 particles are analyzed. Additionally, the relationships between pa...

The general population is exposed to particulate air pollution from many different local and regional sources. Examples of local sources are traffic, biomass burning and resuspended dust, while regional sources are dominated by combustion processes from heating, traffic and industries. The overall aim of this thesis was to characterise the personal exposure to trace elements in fine particles, ...

8 Demolition of buildings produce large quantities of particulate matter (PM) that could be inhaled 9 by on-site workers and people living in the neighbourhood, but studies assessing ambient 10 exposure at the real-world demolition sites are limited. We measured concentrations of PM10 11 (≤10 μm), PM2.5 (≤2.5 μm) and PM1 (≤1 μm) along with local meteorology for 54 working hours 12 over the demo...

Exposure to particulate matter (PM) is a major world health concern, which may damage various cellular components, including the nuclear genetic material. To assess the impact of PM on nuclear genetic integrity, structural chromosomal aberrations are scored in the metaphase spreads of mouse RAW264.7 macrophage cells. PM is collected from ambient air with a high volume total suspended particles ...