In a Web experiment, participants were randomly assigned to 2 semantic differentials either made from discrete 5-point ordinal rating scales or from continuous visual analogue scales (VASs) with 250 gradations. Respondents adjusted their ratings with VASs more often to maximize the precision of answers, which had a beneficial effect on data quality. No side effects like differences in means, hi...

This article presents a review on the existing techniques for manipulating biological cells. Because biomanipulation involves a wide range of disciplines, from biology to engineering, we concentrate on some of the key methodologies that would result in an efficient biomanipulation system. Some of the key methodologies discussed in this article for cell manipulation relate to the use of magnetic...

With wider use of multi drug therapy the milestone of leprosy elimination in India was achieved in December 2005. But as per statistics, around one million leprosy-affected patients with disability are living in India. The national leprosy elimination programme was started in 1983 and leprosy services were integrated into the general health services in 2004, with the aim that leprosy patients w...

Laboratory research has found that individuals will consume more calories and make unhealthy food choices when in the presence of an overweight individual, sometimes even regardless of what that individual is eating. This study expanded these laboratory paradigms to the field to examine how weight salience influences eating in the real world. More specifically, we tested the threshold of the ef...

PURPOSE Three-dimensional (3D) computer-automated threshold Amsler grid testing was used to identify and characterize scotomas typical of glaucoma. METHODS The 3D test exhibits a grid on a computer screen at a preselected grayscale and angular resolution, and allows patients to trace those areas on the grid that are missing in their visual field using a touch screen. Eleven eyes in patients w...

A task-oriented questionnaire was designed, aiming to quickly assess competence with the use of computers. The questionnaire consisted of distinct computer-related skills, representing various competences in educational computer use. A total score from 0 to 49 was calculated upon completion of the questionnaire, based on the sum of all the positively identified competences. The questionnaire wa...

Octopuses are intelligent, soft-bodied animals with keen senses that perform reliably in a variety of visual and tactile learning tasks. However, researchers have found them disappointing in that they consistently fail in operant tasks that require them to combine central nervous system reward information with visual and peripheral knowledge of the location of their arms. Wells claimed that in ...

The term observational study describes a wide range of study designs including prospective and retrospective cohort studies, case-control studies, and cross-sectional studies, a defining feature of which is that any intervention studied is determined by clinical practice and not the protocol. Data from large, prospective observational studies provide information about the safety and efficacy of...

Drug absorption modeling is a task that requires different tools depending on the drug development stage. Scientific progress and increased computer power have initiated a veritable revolution of modeling and simulation. Technical developments have enabled a high model complexity that was unthinkable only a couple of years ago. Today, model simulations can be used to guide experimental planning...

PURPOSE To describe a methodology for establishing signal-to-noise ratios (SNRs) for different perimetric techniques, and to compare SNRs of frequency-doubling technology (FDT2) perimetry and standard automated perimetry (SAP). METHODS Fifteen patients with open-angle glaucoma (median MD, -2.6 dB, range +0.2 to -16.1 dB) were tested six times with FDT2 and SAP (SITA Standard program 24-2) wit...