purpose: to report a case of subretinal fibrosis and uveitis (sfu) in a young man. patient and findings: a 31-year-old man presented with decreased vision without redness or pain or any systemic finding. clinical findings included decreased visual acuity to 3 m cf and trace cell and flare in the anterior chamber and anterior vitreous. there were findings compatible with multifocal choroiditis t...

apoptosis has a critical role in the pathogenesis of bleomycin induced-pulmonary fibrosis. the severity of fibrosis varies among different strains of mice. recent studies have indicated that expression of apoptotic regulatory genes may be specific in different cell types in various strains. in this study, bleomycin-induced pulmonary apoptosis in nmri albino mice were compared with c57bl/6 black...

background since tuberculosis (tb) is a major public health problem that is a leading cause of mortality and morbidity among infectious diseases worldwide, early diagnosis and treatment are important to control an effective tuberculosis (tb) and also the increasing number of patients with atypical manifestations of active tb. it suggests more evaluation for active tb in fibrotic lesion in ct sc...

introduction: pulmonary involvement secondary to systemic sclerosis (ssc) is the major cause of morbidity and mortality in ssc patients. we designed this study to determine the correlation of important lung function parameters with lung high resolution ct (hrct) scan findings.materials and methods: thirty–two consecutive diffuse ssc patients with pulmonary fibrosis were enrolled in this cross-s...

liver fibrosis is a potentially reversible response to hepatic insults, triggered by different chronic diseases most importantly viral hepatitis, alcoholic, and non-alcoholic fatty liver disease. in the course of the chronic liver disease, hepatic fibrogenesis may develop, which is attributed to various types of cells, molecules, and pathways. activated hepatic stellate cell (hsc), the primary ...

conclusions the pattern of longitudinally increased liver stiffness measurements efficiently supported clinical decisions for individualized management strategies. repeated transient elastography in real-life clinical practice appears to have a practical role in monitoring liver transplanted patients. background liver transplanted patients need close surveillance for early signs of graft diseas...

conclusions the incidence of mbls producing p. aeruginosa in patients with cf was not low. the findings indicate that the identification of drug-resistance patterns in p. aeruginosa and the detection of mbl-producing isolates are important in the prevention and control of infections. background respiratory infections caused by pseudomonas aeruginosa play an important role in the pathogenesis of...

congenital hepatic fibrosis (chf) is a developmental disorder of the biliary system, characterized by defective remodeling of the ductal plate. herein a family of three children, from consanguineous parents, with minor thalassemia is presented who suffered from congenital hepatic fibrosis (chf). prompt diagnosis and appropriate treatment are necessary to avoid further complications in the affec...

Background This prospective study was designed to examine the role of fibrosis staging on selection and success of treatment options for autoimmune hepatitis (AIH). Materials and Methods The project was conducted on 110 selected AIH patients who, based on the results of liver biopsy, had been assigned into one of the three groups (mild, stages 1 and 2, moderate, stages 3 and 4, and severe, stag...

conclusions this study revealed that serum iron markers (especially ferritin and transferrin) might be used as surrogate markers for both liver fibrosis and necroinflammatory activity. patients and methods eighty five patients with untreated hepatitis c chronic infection were investigated. . results twenty one patients (24.7%) had elevated serum iron levels, and 29 subjects (34.1%) had severe l...