نتایج جستجو برای: fibroblastic cells
تعداد نتایج: 1384198 فیلتر نتایج به سال:
Abstract During sepsis, massive PAMPs and DAMPs are released initiate the TLR signaling to mediate immune response cell fate decision in cells. We have shown that Fibroblastic Reticular Cells (FRC)-based therapy improves outcome a mouse polymicrobial sepsis model. Modulating TLR4 TLR9 FRC regulates efficacy of FRC-based sepsis. However, whether thus affects is unknown. Here we aim understand ro...
Transcriptional regulatory network (TRN) reconstitution and deconstruction occur simultaneously during reprogramming; however, it remains unclear how the starting and targeting TRNs regulate the induction and suppression of peripheral genes. Here we analyzed the regulation using direct cell reprogramming from human dermal fibroblasts to monocytes as the platform. We simultaneously deconstructed...
Purpose: The aim is to downregulate the expression level of NS as an important factor in sustaining stem cells and certain types of cancer cells self-renewal ability in bone marrow derived mesenchymal stem cells by RNAi strategy and investigate the effects of absence of NS in these cells. Materials and Methods: Double strand NS-specific and control siRNA oligos were designed and transfected in...
IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
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