materials and methods in the present study, a potent nk-producing strain was isolated from cow milk and identified. to enhance the yield of nk, effect of various parameters such as ph, temperature, carbon source, nitrogen source and inoculum size were optimized. strain improvement of p. aeruginosa cmss was done by random uv-mutagenesis. nattokinase was partially purified and the activity was de...

During the past two decades, major advances in the treatment of acute ST-segment elevation myocardial infarction (STEMI), including coronary care units and thrombolysis, have lowered the mortality after hospital presentation to approximately 5%. However, in recent years, there has been little further improvement in survival (1). Neither newer fibrinolytic agents nor attempts to combine a reduce...

The possibility that intra-arterial local infusion of fibrinolytic agents may achieve recanalization of previously occluded carotid territory arteries in acute stroke was tested in a prospective angiography-based open pilot study at two centers. Fifteen of 20 patients with acute symptoms (mean treatment-onset interval 7.6 hours) demonstrated complete recanalization; 10 of the 15 patients exhibi...

Coagulation A bnormalities in Subarachnoid Hemorrhage • Coagulation and fibrinolytic studies were performed in 30 subarachnoid hemorrhage patients and 30 age-matched and sex-matched controls. Systemic abnormalities were detected in the following tests: recalcification time, fibrinogen, partial thromboplastin time, K value of thromboelastogram and euglobulin lysis time. The data suggest that sub...

Resting fibrinolytic activity and the response of the fibrinolytic system to venous occlusion were studied in a group of healthy middle-aged men. All subjects showed increased fibrinolytic activity but of varying degrees. There was a linear relationship between resting and occluded levels of fibrinolytic activity but many subjects with lower levels of fibrinolytic activity showed an anomalous r...

Postsurgical adhesions are a common complication of surgical procedures that can lead to postoperative pain, bowel obstruction, infertility, as well complications with future procedures. Several agents have been developed prevent adhesion formation, such barriers, anti-inflammatory and fibrinolytic agents. The Food Drug Administration (FDA) has approved the use physical barrier agents, but they...