The presented work depicts results of a two-scale approach to the problem of damage and failure prediction on laminated composite structures. Modeling on the micro-level has enabled insight into the underlying physical processes which lead to homogenized properties of the macro-scale material. In this work, micromechanical analysis has been performed by application of the High Fidelity Generali...

The main objective of this study is to design titanium alloy femoral stems with cubic porous structures that will be able reduce stress shielding and promote stem stability. These structure designs were introduced into as homogeneous functionally graded structures. First, the cellular simulated under compressive loading measure yield modulus elasticity for various porosity ranges. Based on sele...

A damage identification technique based on frequency response functions (FRF) sensitivities is presented. This technique leads to a set of linear equations, which is solved using an algorithm that constrains the solution to be physically admissible. Damage simulation and identification on a laminated rectangular plate is performed. The influence of the number of natural frequencies and mode sha...

A first mesomodelling, which allows us to describe the mechanical behaviour of an elementary ply within a SiC-SiC laminate under dynamic loading, is proposed. Questions related to its identification and its use for the prédiction of the dynamic fracture of laminated structures are discussed.

The susceptibility genes for schizophrenia Neuregulin-1 (NRG1) and ErbB4 have critical functions during brain development and in the adult. Alterations in the ErbB4 signaling pathway cause a variety of neurodevelopmental defects including deficiencies in neuronal migration, synaptic plasticity, and myelination. I have used the ErbB4(-/-) HER4(heart) KO mice to study the neurodevelopmental insul...