BACKGROUND Postnatal outcome of fetuses with hypoplastic left heart syndrome (HLHS) is mainly determined by right ventricular function. In the present study we used spatio-temporal image correlation (STIC) to assess right ventricular function of fetuses with HLHS. METHODS Three-dimensional ultrasound with STIC technique was used to acquire heart images from fetuses that had HLHS and the norma...

OBJECTIVE To compare the volume of the ipsilateral and contralateral lungs in fetuses with congenital diaphragmatic hernia (CDH). METHODS Left and right lung volumes were measured using three-dimensional (3D) ultrasonography in 42 fetuses with CDH at median 26 (range, 20-32) weeks of gestation. Each value was then expressed as a difference, in standard deviations, from the normal mean for ges...

Mustafa, Shamimunisa B., Robert J. DiGeronimo, Jean A. Petershack, Joseph L. Alcorn, and Steven R. Seidner. Postnatal glucocorticoids induce -ENaC formation and regulate glucocorticoid receptors in the preterm rabbit lung. Am J Physiol Lung Cell Mol Physiol 286: L73–L80, 2004. First published August 29, 2003; 10.1152/ajplung.00342.2002.—At birth, lung fluid clearance is coupled to Na transport ...

Glucose intolerance in adults born with intrauterine growth retardation (IUGR) may involve peripheral insulin resistance and/or abnormal endocrine pancreas development during fetal life. We quantified insulin-containing cells in deceased human fetuses with IUGR (<10th percentile, n = 21) or normal growth (control fetuses, n = 15). Paraffin-embedded pancreatic tissues from fetuses older than 32 ...

OBJECTIVES The aim of this study was to investigate whether there is an association between enlarged nuchal translucency (NT) and orofacial clefts. METHODS The pregnancy outcome of women who underwent an NT measurement between January 2000 and November 2008 was reviewed. All orofacial clefts detected prenatally and postnatally in karyotypically normal fetuses/infants were reviewed and a disti...

BACKGROUND Parvovirus B19 infection during pregnancy can lead to nonimmune fetal hydrops, miscarriage, and intrauterine fetal death (IUFD). Some studies have suggested that parvovirus B19 infection may surprisingly often result in nonhydropic fetal death during the third trimester, in the absence of maternal serological evidence of acute infection. This study was conducted to investigate the pr...

Treatment of lactating and nonlactating parous cows (n = 379) with 12 mg of FSH-P to evaluate development of multiple bovine fetuses resulted in ovulation rates ranging from 1 to 27 corpora lutea (CL). Fertilization rate (i.e., ova fertilized at 6 to 8 d postmating, 80.0%) was not affected by ovulation rate. The percentage of fetuses developing normally at 51 to 53 d postmating decreased (P les...

Objective The purpose of this study was to evaluate ductus venosus fl ow velocities and a possible relationship with the type of cardiac defect in fetuses with increased nuchal translucency (NT). Methods Seventy-two fetuses with normal NT and 137 fetuses with increased NT (>95th percentile) were evaluated. The ductus venosus pulsatility index for veins (PIV), late diastolic velocity (velocity d...

OHMANN, H. BIELEFELDT: Immunoglobulin levels in non-aborted and aborted fetuses from Danish herds of cattle. Acta vet. soancl. 1981, 22, 428-434. The applicability of serological tests in the diagnosis of intrauterine infections in Danish cattle was investigated. Fetuses from slaughter animals, experimentally infected and spontaneously aborted fetuses, premature and stillborn calves, were subje...

Introduction. Vascular endothelial growth factor (VEGF), an angiogenic factor secreted by type II pneumocytes, could play a role in congenital diaphragmatic hernia (CDH) pathogenesis. Animal studies suggest that VEGF accelerates lung growth. Aim. To quantify VEGF on fetal lungs in a nitrofen rat model for CDH and to analyze the effect of tracheal occlusion (TO) in VEGF in fetal lung rats after ...