Aim: Determination of fetal gender by palpating the intensity maternal pulse on right and left 5th finger, based Ayurvedic principle that there is a ‘nadi’ (a pathway or channel in human body) connecting pregnancy finger. Methods: 130 pregnant women from Obstetrics Pathology Department-UCK, Gdansk, Poland were included study. Twin pregnancies excluded. The finger was palpated followed palpation...

Key content Fetal placental mosaicism, of which confined mosaicism is a subtype, occurs in 2–3% pregnancies. Confined may lead to false positive result on non-invasive prenatal testing (NIPT) for common aneuploidies. The risk chorionic villus sample (CVS) following NIPT 2, 4, 22 and 59% trisomy 21, 18, 13 45, X respectively. Following the absence significant fetal structural anomaly (FSA), care...

INTRODUCTION Exposure to prenatal inflammation is associated with diverse adverse neurobehavioral outcomes in exposed offspring. The mechanism by which inflammation negatively impacts the developing brain is poorly understood. Metabolomic profiling provides an opportunity to identify specific metabolites, and novel pathways, which may reveal mechanisms by which exposure to intrauterine inflamma...

To investigate the effect of intrauterine positions on fetal growth throughout gestation, data from a total of 65 gilts (n = 784 fetuses) that were slaughtered at assigned days of gestation (d 43, 58, 73, 91, 101, and 108) on a project to evaluate fetal mineral deposition were used. Placenta units were removed from the uterus, and position, sex, weight, and crown-rump length (CRL) of each fetus...

Dizygotic compared with monozygotic conceptions are at decreased risk of fetal and infant death and serious morbidity in surviving infants. Different sex twin maternities must be dizygotic but miscoding and incorrect registration of sex and number of fetuses may lead to an incorrect assignment of zygosity. The aim of the study was to validate the coding and registration of number and sex of bir...

The impact of prenatal smoke exposure (PSE) on DNA methylation has been demonstrated in blood samples from children of smoking mothers, but evidence for sex-dependent smoke-induced effects is limited. As the identified differentially methylated genes can be associated with developmental processes, and insulin-like growth factors (IGFs) play a critical role in prenatal tissue growth, we hypothes...

The accuracy of targeted cell-free DNA (cfDNA) testing with DANSRTM and FORTETM for trisomies 21, 18 and 13 has been well demonstrated and is consistent across next generation sequencing and microarray quantitation methods1. Targeted cfDNA analysis for fetal sex chromosome aneuploidy (SCA) has also been validated and shown to have high specificity in prospective studies2,3. This study expands u...

Mammals, including humans, show sex differences in juvenile play behavior. In rodents and nonhuman primates, these behavioral sex differences result, in part, from sex differences in androgens during early development. Girls exposed to high levels of androgen prenatally, because of the genetic disorder congenital adrenal hyperplasia, show increased male-typical play, suggesting similar hormonal...