Objective To investigate whether an adjuvanted pandemic A/H1N1 2009 influenza vaccine in pregnancy was associated with an increased risk of fetal death. Design Nationwide register based cohort study. Setting Denmark. Participants All clinically recognised singleton pregnancies that ended between November 2009 and September 2010. Individual level data on exposure to an inactivated AS03 pandemic ...

Background: Fetal death (stillbirth), that occurs every 100-200 pregnancies in industrialized countries, has not significantly decreased in recent years, mostly because of scarce research activities in this field. Fetal death is often, in up to 60-80% of cases, unexplainable, even after routine diagnostic examinations. Objectives: This work aims to stress the importance of in-depth histopatholo...

OBJECTIVE To investigate whether an adjuvanted pandemic A/H1N1 2009 influenza vaccine in pregnancy was associated with an increased risk of fetal death. DESIGN Nationwide register based cohort study. SETTING Denmark. PARTICIPANTS All clinically recognised singleton pregnancies that ended between November 2009 and September 2010. Individual level data on exposure to an inactivated AS03 pan...

background: due to increase in pregnancy complications in advanced age, this study was conducted to assess the relationship between advanced maternal age and the pregnancy complications. methods: pregnant women who admitted to the motazedi hospital in kermanshah were included in this analytic–cross sectional study. the study group was 1178 cases that divided into two sub-groups; 35-40 year-old ...

The incidence of pregnancy outcomes in women with constitutive thrombophilia is uncertain. We observed women with no history of thrombotic events (nonthrombotic), who had experienced 3 consecutive spontaneous abortions before the 10th week of gestation or 1 fetal death at or beyond the 10th week of gestation. We compared the frequencies of complications during a new pregnancy attempt among wome...

The antiphospholipid syndrome (APS) is associated with thrombosis and fetal death but the pathologic mechanisms are poorly understood. Since endothelial protein C receptor (EPCR) plays a role in the anticoagulant system and in placental development, we hypothesized that anti-EPCR autoantibodies may be involved in clinical manifestations of APS and in fetal loss. The levels of immunoglobulin M (...