نتایج جستجو برای: ferrets
تعداد نتایج: 2317 فیلتر نتایج به سال:
27 During the last two decades ferrets (Mustela putorius) have been established as a highly 28 efficient animal model in different fields in neuroscience. Here we asked whether ferrets 29 integrate sensory information according to the same principles established for other species. 30 Since only few methods and protocols are available for behaving ferrets we developed a 31 head-free, body-restra...
The black-footed ferret (Mustela nigripes) is an endangered North American carnivore that underwent a well-documented population bottleneck in the mid-1980s. To better understand the effects of a bottleneck on a free-ranging carnivore population, we used 24 microsatellite loci to compare genetic diversity before versus during the bottleneck, and compare the last wild population to two historica...
Infection with Helicobacter pylori has been associated with induction of autoantibodies that cross-react with the gastric mucosa. There have been discordant reports as to whether or not these autoantibodies arise due to molecular mimicry between H. pylori and host cell antigens on parietal cells. In this study, we investigated whether molecular mimicry by H. mustelae causes autoantibodies in in...
—The black-footed ferret (Mustela nlgrlpes) was once widely distributed in the Great Plains and intermountain valleys of North America, its range overlapping the combined ranges of several species of prairie dogs (Cynomys spp.). Most life history information has been obtained from studies of ferrets in southwestern South Dakota (1964-1974) and studies near Meeteetse, Wyoming (1981-present). The...
The neurovirulence of two wild type (wt) and seven Subacute Sclerosing Panencephalitis (SSPE) measles virus strains was tested in young adult ferrets by intracerebral (IC) inoculation of infected Vero cell suspensions. Wt strains Edmonston and Woodfolk and SSPE strains Mantooth, Halle, and LEC-S did not produce a detectable encephalitis in the ferrets, but caused a significant formation of seru...
Efficacy of oseltamivir therapy in ferrets inoculated with different clades of H5N1 influenza virus.
Highly pathogenic H5N1 influenza viruses have infected an increasing number of humans in Asia, with high mortality rates and the emergence of multiple distinguishable clades. It is not known whether antiviral drugs that are effective against contemporary human influenza viruses will be effective against systemically replicating viruses, such as these pathogens. Therefore, we evaluated the use o...
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza interventions and vaccines. The 2009 pandemic influenza virus (H1N1pdm09) induces mild to moderate respiratory disease in infected ferrets, following inocu...
Highly pathogenic avian influenza A (HPAI), subtype H5N1, remains an emergent threat to the human population. While respiratory disease is a hallmark of influenza infection, H5N1 has a high incidence of neurological sequelae in many animal species and sporadically in humans. We elucidate the temporal/spatial infection of H5N1 in the brain of ferrets following a low dose, intranasal infection of...
BACKGROUND Proteus mirabilis is an important uropathogen that causes complicated Urinary Tract Infection (UTI) and induces diarrhea in infants. OBJECTIVES This study aimed to investigate P. mirabilis infection in newly weaned infant rhesus monkeys (Macaca mulatta) and ferrets (Mustela putorius furo) with diarrhea. MATERIALS AND METHODS Stool samples were collected from 74 rhesus monkeys and...
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