The carcinogenic potential of tilidine fumarate, a synthetic analgesic, was studied for 80 and 104 weeks in mice and rats, respectively. Groups of 50 albino CF1 mice and 65 albino Wistar rats of each sex received tilidine fumarate-lactose blend (1:1) at doses of 100, 40 and 16 mg/kg. The control groups consisted of 100 mice and 115 rats of each sex and received the lactose vehicle only. Treatme...

The effect of Bony Light Crude Oil (BLCO) on some sperm functions during short term exposure has been reported. The present study investigated the effect of long term ingestion of BLCO on fertility indices in male and female albino rats. Adult male rats in groups of five were exposed daily to 0, 200, 400 and 800 mg/kg BLCO (orally, p.o) dissolved in olive oil which served as the control, for si...

This study investigated the toxicity of sodium fluoride on male reproductive hormones and ameliorative effects extract Phyllantus amarus adult albino rats. The consisted six equal groups five rats that were administered with over a period two weeks. result indicates possible hormone lipid profile probable capacity to ameliorate this toxicity.

In this study, 40 female albino wistar rats were used. The sciatic nerves were crushed for 20 seconds by a jeweler’s forceps. A single dose of 8 mg/kg of trapidil was administered to the treatment group intraperitoneally. After the crush injury, the crush site was excised on 2nd, 7th, 15th, 30th, and 45th days, fixed in formalin and then prepared for routine histological evaluation. Each sectio...

Pitirrunthos /rirudiutir.s is a common perennial in the Negev desert and although its dense tufts are green all the year, it only occasionally is grazed by goats or gazelles (D. Ashkenazy, personal communication). Five furocoumarins were detected in the shoots of this plant.’ Some furocoumarins present in different members of the Umbelliferae are known to induce photosensitization in various an...

Hoarding pattern studied in 28 adult female albino rats indicated cyclic changes in hoarding corresponding to alterations in estrus cycle. It was observed that the hoarding score was maximum at proestrus and the least at diestrus. Animals ovariectomised at proestrus maintained higher hoarding score and those ovariectomised at diestrus stablised on lower hoarding score. Progesterone administrati...

Abstract Decreasing the salivary flow rate manifested by xerostomia occurs early during irradiation treatment. The duration of depressed function varies among patients. Various histopathological changes occur in glands. current study was performed to investigate and compare between possible anti-radiotherapeutic effect gamma rays-synthesized curcumin nanoparticles (Cur NPs), chitosan (Cs NPs). ...