In this study, the adsorption behavior of anionic dyes from aqueous solution onto mesoporous carbon material (CMK-1) and modified with polymer (PANI/CMK-1) has been investigated as a function of parameters such as adsorbent dose (0.08-0.8 g/L), solution pH 3–10, contact time and initial concentration (10-100 mg/L). The influence of these parameters on the adsorption capacity has been studied us...

In subacute cutaneous lupus eryhematosus (SCLE) the cutaneous antigens constitute the main source of Ro and La autoantigens. The aim of this investigation was to demonstrate if UV light increases the availability of Ro autoantigen in the skin, also the blocking effect of Ac-DEVD-CMK a caspase inhibitor was assessed. For this purpose newborn Balb/c mice were UVB irradiated (5-30 mJ/cm(2)) equiva...

Mesoporous silica- and carbon-based materials, including bioactive glasses, have proven potential as components of medical devices drug carriers. From an application perspective, knowledge about the shelf-life stability these materials under various conditions is vital. Here, mesoporous glasses (MBGs) synthesized by aerosol-assisted spray-drying a batch sol–gel method, silicas SBA-15 type, carb...

Four types of carbons (activated carbon, Maxsorb superactivated carbon, mesoporous templated carbon CMK-3, and graphene) were investigated as selective sorbents for adsorption of thiophene from its solution in n-octane. Graphene showed clearly the highest sulfur capacity. The relative sulfur capacities correlated well with the relative heats of adsorption. The carbene-type zigzag edge sites and...

Dracorhodin perchlorate inhibited proliferation of several tumor cell lines. The drug induced oligonucleosomal fragmentation of DNA in HeLa cells and increased caspase-3, -8, -9 activities followed by the degradation of caspase-3 substrates, inhibitor of caspase-dependent DNase, and poly-(ADP-ribose) polymerase. It also increased caspase-1 activity and a caspase-1 inhibitor, Ac-YVAD-cmk, and a ...

Down syndrome children with acute megakaryocytic leukemia (AMkL) have higher cure rates than non-Down syndrome acute myeloid leukemia (AML) patients treated with cytosine arabinoside (ara-C). Megakaryoblasts from Down syndrome AML patients are more sensitive in vitro to ara-C than cells from non-Down syndrome AML patients. Somatic mutations in the GATA1 transcription factor have been detected e...

Activation of the mitogen-activated protein (MAP) kinase pathway has been associated with both cell proliferation and differentiation. Constitutively activated forms of Mek (MAP kinase/Erk kinase) and Erk (MAP kinase) have been previously shown capable of inducing differentiation or proliferation in nonhematopoietic cells. To specifically examine the role of Erk activation in megakaryocytic gro...