Possibility of existence microheterogeneous states in Fe – Mn C melts was analyzed carried out according to the concepts chemical thermodynamics. Microheterogeneous state a chemically inhomogeneous melt understood as presence dispersed particles it, which are suspended environment and separated from it by interface. Hypothesis is supported numerous experimental data on their thermodynamic physi...

Recent studies of cardiac and skeletal muscle suggest that the sites at which Mn uncouples excitation and contraction are restricted to a space functionally equivalent to the interstitium. We sought to corroborate this hypothesis by using the ferrocyanide anion, Fe(CN)j{~. This anion is relatively innocuous to myocardial tissue, is compatible with solutions containing alkaline and alkaline eart...

We demonstrate a new strategy for tuning the size of large-diameter and few-walled nitrogen-doped carbon nanotubes (N-CNTs) from 50 to 150 nm by varying the transition metal (TM = Fe, Co, Ni or Mn) used to catalyze graphitization of dicyandiamide. Fe yielded the largest tubes, followed by Co and Ni, while Mn produced a clot-like carbon morphology. We show that morphology is correlated with elec...

Iron (Fe) and copper (Cu) metabolism are closely intertwined, and a deficiency of Cu may lead to a secondary Fe deficiency. The impact of a severe Cu deficiency on proteins involved in Fe metabolism in the bovine has not been studied. Therefore, a 493 day study was conducted to determine the effect of a severe long-term Cu deficiency on Fe metabolism in beef cattle. Twenty-one Angus calves were...

BACKGROUND Manganese (Mn) is widely used in industries including the manufacture of Mn-iron (Fe) alloy. Occupational Mn overexposure causes manganism. Mn is known to affect Fe metabolism; this study was designed to test the hypothesis that workers exposed to Mn may have an altered expression of mRNAs encoding proteins in Fe metabolism. METHODS Workers occupationally exposed to Mn (n = 71) fro...

Our previous studies show that manganese (Mn) exposure inhibits aconitase, an enzyme regulating the proteins responsible for cellular iron (Fe) equilibrium. This study was performed to investigate whether Mn intoxication leads to an altered cellular Fe homeostasis in cultured neuronal or neuroglial cells as a result of disrupted Fe regulation. Our results reveal a significant increase in the ex...

Manganese (Mn(2+)) neurotoxicity from occupational exposure is well documented to result in a Parkinson-like syndrome. Although the understanding of Mn(2+) cytotoxicity is still incomplete, both Mn(2+) and Fe(2+) can be transported via the divalent metal transporter 1 (DMT1), suggesting that competitive uptake might disrupt Fe(2+) homeostasis. Here, we found that DMT1 overexpression significant...

We investigate the impact of hyperfine splitting on stellar abundance analyses of Mn and Sc, and find that incorrect hfs treatment can lead to spurious abundance trends with metallicity. We estimate corrections to a recent study by Nissen et al. (2000), and find: (1) [Mn/Fe] is described by a bimodal distribution, with [Mn/Fe] ∼ −0.3 for stars [Fe/H] < −0.7, and [Mn/Fe] ∼ −0.05 for stars at hig...