Glucose-6-phosphate dehydrogenase (G6PD) enzyme catalyses the first step in pentose phosphate pathway (conversion of glucose-6-phosphat to 6-phospho gluconat) which provides cells with pentoses and reduction power in the form of NADPH. In the present study we have analyzed the G6PD gene mutations in 76 patients with a history of favism in Khorasan province in Iran. DNA samples were analyzed for...

AIM To determine the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in the population of the town of Komiza on the island of Vis, which has previously been reported as a place with several cases of favism. METHODS We screened 302 randomly selected men, using the fluorescent spot test. Fluorescence readings were performed at the beginning and 5, 10, and 20 minutes after incu...

glucose-6-phosphate dehydrogenase (g6pd) in humans is an x-chromosome-linked disorder and housekeeping enzyme, vital for the survival of every cell. it catalyses the oxidation of glucose-6-phosphate to 6-phospho gluconate in the first committed step of the pentose phosphate pathway, which provides cells with pentoses and reducing power in the form of nadph. nadph is required to protect the cell...

in order to explore the nature of glucose-6-phosphate dehydrogenase (g6pd) deficiency in one of the coastal provinces of the caspian sea (mazandaran) in iran, we have analysed the g6pd gene in 74 unrelated g6pd-deficient males (2-6 year children) with a history of favism, by using pcr and subsequent digestion by appropriate restriction enzymes, looking for the presence of certain known mutation...

Background and aims: G6PD deficiencies is a genetically issue that is noticed and is wide spread in our region and around the world. Despite the screening program for this disease since 2005 there are noticeable cases. Methods: In this descriptive study the file of 923 patients that were diagnosed with Favism and hospitalized in Khorramabad hospitals during 2005 and 2015 were reviewed. This inf...