BACKGROUND Pharmacologic activation of the peroxisome proliferator-activated receptor gamma (PPAR-gamma) improves ovulatory function in women with polycystic ovary syndrome, and specific dietary fatty acids can affect PPAR-gamma activity. OBJECTIVE The objective of the study was to assess whether the intakes of total fat, cholesterol, and major types of fatty acids affect the risk of ovulator...

Background and Objectives: Breast milk composition is affected by several factors such as maternal diet and body mass index. Milk fats include a major calorie content of the milk, which changes dramatically throughout the lactation. The aim of the present study was to assess breast milk fatty acid profile in overweight and obese mothers and its correlations with maternal body mass index. Mater...

The properties of the depot fats of animals depend, to some extent, upon the nature of the dietary fats. Thus it was shown by Anderson and Mendel (1) that feeding of highly unsaturated oils results in the deposition of a body fat of high iodine number, whereas the administration of “hard” fat in the diet leads to a decrease in the iodine number of the depot fats. Recently Longenecker and Hildit...

The presence of medium-chain fatty acids in dietary fatty acid as well as the triacylglycerol structure may influence the absorption and lymphatic transport of fatty acids. We compared the lymphatic transport and recovery of fatty acids from four intragastrically administered fats based on rapeseed oil and decanoic acid in two rat models of normal absorption and malabsorption, respectively. The...

Statistical techniques have been used to establish the extent to which the incidence of spontaneous mammary tumors in C3H mice could be associated with the levels of individual fatty acids in their diets. Eleven different fats and oils and nine mixtures of these fats and oils were selected so that the levels of the nine major fatty acids varied over a reasonable range and were not highly correl...

Depression is a complex disorder influenced by a variety of biological and environmental factors. Due to significant heterogeneity, there are remarkable differences in how patients respond to treatment. A primary objective of psychiatric research is to identify biological markers that could be used to better predict and enhance responses to antidepressant treatments. Diet impacts various aspect...

According to various studies, fats of animal and vegetable origins satisfy 22% to 42% of the daily energy demands of human beings (Srinivasan et al., 2006; Wagner et al., 2008; Willet, 2006). Some fats, and especially those that are hydrogenated, contain trans fatty acids (TFAs), i.e. unsaturated fatty acids with at least one double bond in a trans configuration (Craig-Schmidt, 2006). This tran...