conclusions our study showed that arm is a useful approach in determining which combinations of variables or predictors occur together frequently, in people who will develop diabetes. the arm focuses on joint exposure to different combinations of risk factors, and not the predictors alone. background type 2 diabetes, common and serious global health concern, had an estimated worldwide prevalenc...

objective: this study evaluated the efficacy and safety of metformin on prevention of gestational diabetes mellitus in women with high risk of gdm. materials and methods: total number of 189 pregnant women aged between 25 to 35, and 10 to 14 weeks pregnancy,admitted to  mirza koochakkhan hospital, tehran in january 2008 - january 2009 entered to this randomized controlled clinical trial. the wo...

OBJECTIVE Children of affected probands are at increased risk for type 1 diabetes. The objective of this study was to determine and stratify the risk for islet autoimmunity and childhood diabetes in newborn offspring of affected parents using family history and HLA genetic markers. RESEARCH DESIGN AND METHODS Antibodies to islet autoantigens were measured at ages 9 months, 2 years, 5 years, a...

background : type 1 diabetes mellitus is the most common endocrine disease in pediatric. we aimed to determine the demographic characteristics at presentation of childhood type 1 diabetes mellitus in hamadan, west province of iran. methods : in this cross sectional descriptive study, demographic data of children with type 1 diabetes mellitus being followed up in pediatric endocrinology clinic o...

Genetic association studies have identified more than a dozen genes associated with risk of pancreatic cancer. Given this genetic heterogeneity, family history can be useful for identifying individuals at high risk for this disease. The goal of this analysis was to evaluate associations of family history of diabetes and family history of pancreatic cancer with risk of pancreatic cancer. PACIFIC...

abstract objective: patients with type 2 diabetes mellitus (dm) have a markedly increased risk of cardiovascular morbidity and mortality. there are some recommendations for prescription of aspirin in these patients. our purpose was to determine aspirin usage rate in diabetic patients and to compare it in different ages and based upon cardiovascular disease (cvd) risk factors. materials and meth...

OBJECTIVE To assess the family history of diabetes in type 2 black South African diabetics with emphasis on the parental phenotype. DESIGN Prospective case-control study in which family histories were obtained from patients. SETTING Diabetic clinic of a provincial teaching hospital in the Transkei region of South Africa. SUBJECTS A total of 1111 type 2 diabetics attending the diabetic cli...

Always granting that de novo mutations are possible, family history and biological characteristics are nonetheless crucial for the diagnosis of monogenic diabetes. We report here the case of two patients with monogenic diabetes in which the initial family history misled the diagnostic work-up and did not support the diagnosis. Family history details changed substantially after the molecular dia...

objective: this study aimed to determine the association of cardiac risk factors and the risk of acute myocardial infarction (ami) in emergency department (ed) patients with non-diagnostic ecg changes. methods: this cross-sectional study was conducted in the ed of imam hossein hospital during a period of one year. in this study, patients with symptoms suggestive of ami including chest pain, dys...