Members of the interferon-regulatory factor (IRF) proteins family were originally identified as transcriptional regulators of the Type I interferon system. Thanks to consistent advances made in our understanding of the immunobiology of innate receptors, it is now clear that several IRFs are critical for the elicitation of innate pattern recognition receptors, and-as a consequence-for adaptive i...

Family factors have been reported to influence the course of schizophrenia. In a replication of British studies, schizophrenic patients from the Los Angeles area were evaluated for symptomatic relapse 9 months after hospital discharge as a function of the level of "expressed emotion" in their relatives. In striking confirmation of the British findings, patients who came from families that were ...

CudA, a nuclear protein required for Dictyostelium prespore-specific gene expression, binds in vivo to the promoter of the cotC prespore gene. A 14 nucleotide region of the cotC promoter binds CudA in vitro and ECudA, an Entamoeba CudA homologue, also binds to this site. The CudA and ECudA DNA-binding sites contain a dyad and, consistent with a symmetrical binding site, CudA forms a homodimer i...

background: the study was developed in order to find a subset of potential factors, which affect birth distance pattern, regarding consideration on correlation of events of birth in a family and correlation within clusters/centers which other studies omit these correlations. methods: referring to documents that were registered for family in the health care centers on socio-economical zone, we c...

The purpose of the present study was to evaluate the impact of different family factors on juvenile delinquency. Specifically, this thesis examined parental monitoring, attachment to parents, and family structure by investigating their single and combined effects on delinquency. In addition, the current study addresses the effects family factors have on different levels of delinquent behavior. ...

The ability to regulate and even target mutagenesis is an extremely valuable cellular asset. Enzyme-catalyzed DNA cytosine deamination is a molecular strategy employed by vertebrates to promote antibody diversity and defend against foreign nucleic acids. Ten years ago, a family of cellular enzymes was first described with several proving capable of deaminating DNA and inhibiting HIV-1 replicati...

one of recent developments in modern societies is the evolution in the structure of power division in the family and changes in reciprocal actions between wife and husband. this research aims to study the factors affecting distribution of power in the family by using the theories of: social capital, valuable resources, and sociability of gender. the data has been collected through survey method...