BACKGROUND Schizophrenia is a complex psychiatric disorder characterized by high phenotypic heterogeneity. Previous studies have distinguished between familial and sporadic forms of schizophrenia and have suggested clinical differentiation between patients and relatives from sporadic and multiplex families. We will introduce a more refined method to distinguish between family subtypes based on ...

Humans as social beings must have experienced a contradiction or dispute. In the daily life of many people who experience conflicts, both in real and literary works such theater, film, novel, so on. This research is motivated by number conflicts novel characters are no exception to About You. The approach used this sociology literature. Sociology literature an analyzing that talk about relation...

The Dlg1 gene encodes a member of the MAGUK protein family involved in the polarization of epithelial cells. Null mutant mice for the Dlg1 gene (Dlg1-/- mice) exhibit respiratory failure and cyanosis, and die soon after birth. However, the cause of this neonatal lethality has not been determined. In the present study, we further examined Dlg1-/- mice and found severe defects in the cardiovascul...

CONTEXT Factor analysis of the signs and symptoms of schizophrenia yields dimensional phenotypes that may relate to underlying genetic variation. Examination of familiality of factor scores can demonstrate whether they are likely to be of use in genetic research. OBJECTIVE To produce a broader set of factorial phenotypes that are tested for familiality including core symptoms of schizophrenia...

The Neu (ErbB2, HER2) member of the epidermal growth factor receptor family is implicated in many human breast cancers. We have tested the importance of increased angiogenic signaling in the NeuYD [mouse mammary tumor virus (MMTV)-Neu(ndl)-YD5] mammary tumor model. Transgenic mice expressing vascular endothelial growth factor (VEGF)(164) from the MMTV promoter were generated. These mice express...

George Floyd’s murder by a Minnesota police officer sparked outrage, protests, and re-evaluation of racial inequities in America. Within criminology, we argue, that should include the Latino Paradox, idea communities are an exception—a paradox—in that, while they face economic deprivation, also possess magical something makes them resistant to social problems like crime. Unfortunately, this com...

To date, no prior research has examined the combined roles of childhood family adversity and pubertal timing in longitudinal pathways to depressive symptomatology in adulthood. The present study was conducted with 225 men and 225 women to explore the unique and combined roles of childhood family adversity and pubertal timing on depressive symptoms in a community sample of married adults. Result...

MANY studies of mental fatigue have been governed by the expectation that its effects were to be found in a decline in the quantity or quality of the output, and tests have been employed in them involving the repetition of elementary operations. Bartlett (1943) contended, however, that effects related to real life were to be found in the disorganization of skilled activities, of which the work ...

Affiliations 1 Center for Applied Neuroscience, Department of Psychology, University of Cyprus, Nicosia, Cyprus 2 Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom 3 Department of Neuroscience, University of California, San Diego, San Diego CA, USA 4 Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA,...

Little is known about attachment security and disorganization in children who are at genetic risk for an Autism Spectrum Disorder (ASD) prior to a possible diagnosis. The present study examined distributions of attachment security and disorganization at 15-months of age in a sample of infant siblings of older children with (ASD-sibs; n = 51) or without (COMP-sibs; n = 34) an ASD. ASD-sibs were ...