Langerhans cell histiocytosis is a disease primarily affects the bone. More than 50 percent of the disease occurs between the age of 1 and 15. We reported a case of a 2 year old boy who presented with a gluteal mass. Radiographic imaging showed an osteolytic lesion suspicious of malignancy. However, the histological diagnosis was Langerhans cell histiocytosis.

Pulmonary disease in the 'histiocytosis syndromes' is not uncommon. Isolated pulmonary histiocytosis, however, is rarely diagnosed. We describe three patients with this condition, with ages ranging from 3 weeks to 9 1/2 years, in whom there was no evidence of disease in any other organ. Their presentation, treatment, and clinical progress over three years of follow up are discussed.

Keeling, J. W., and Harries, J. T. (1973). Archives of Disease in Childhood, 48, 350. Intestinal malabsorption in infants with histiocytosis X. An infant with histiocytosis X had unequivocal evidence of intestinal malabsorption which was associated with histiocytic infiltration of the small intestine. 11 other fatal cases where histological material from the gastrointestinal tract was available...

We report Langerhans cell histiocytosis involving the sphenoid sinus and extending to the orbital apex. MR and CT imaging, particularly with contrast, both were helpful in defining the extent of the lesion before treatment. MR was a useful examination for follow-up after treatment. Langerhans cell histiocytosis should be considered in the differential diagnosis of lesions of this region in the ...

Malignant histiocytosis (histiocytic medullary reticulosis) in a 45-year-old white man is described. Unusual features were presentation as a surgical emergency with signs of obstruction and peritonitis due to an ileal tumour and extensive spindle cell differentiation. Problems in the differential diagnosis of malignant histiocytosis are briefly discussed.

Pulmonary Langerhans cell histiocytosis is a rare interstitial lung disease. It's morbidity is estimated at 4-5 person per million. The multiformity--from benignity to severe--brings difficulties during the process of diagnosis. The authors describe a case of 48-year-old woman with a benign pulmonary lung histiocytosis. It is underlined the diagnostic quality of high resolution tomography and b...

Severe skin involvement complicated a case of sinus histiocytosis with massive lymphadenopathy in a young Malay girl. The clinical and histological features of this rare manifestation are described.