The soil-borne plant pathogen Fusarium oxysporum causes life-threatening invasive fusariosis in immunocompromised individuals. The mechanism of infection in mammalian hosts is largely unknown. In the present study we show that the symptoms of disseminated fusariosis caused by F. oxysporum in immunosuppressed mice are remarkably similar to those reported in humans. Distinct fungal structures wer...

Soilborne fungal pathogens cause devastating yield losses and are highly persistent and difficult to control. During the infection process, these organisms must cope with limited availability of iron. Here we show that the bZIP protein HapX functions as a key regulator of iron homeostasis and virulence in the vascular wilt fungus Fusarium oxysporum. Deletion of hapX does not affect iron uptake ...

The components of the root exudates from two transgenic insect-resistant cotton lines and their parental cotton lines, and their effects on the growth of Fusarium oxysporum were investigated. The results demonstrated that the resistance of transgenic insect-resistant cotton to F. oxysporum was significantly reduced compared with their parental lines. Likewise, the root exudates from transgenic ...

In the present study we first report in Korea the identification and characterization of Fusarium oxysporum isolated from rotten stems and roots of paprika (Capsicum annuum var. grossum) at Masan, Kyungsangnamdo in 2006. The fungal species produced white aerial mycelia accompanying with dark violet pigment on PDA. The optimal temperature and pH for the growth of the species was 25℃ and pH 7, re...

An antifungal lipopeptide iturin A with strong activity against Fusarium oxysporum was produced by honey isolated strain Bacillus amyloliquefaciens BH072. For large-scale biocontrol application, the antifungal effect was deeply demonstrated by structure and mode of action. Cyclic structure and second structure were determined based on situ acid hydrolysis and Fourier Transformed-Infra Red (FT-I...

Nine different Fusarium species were isolated from Acacia koa seeds, seedpods, seedling stem and root tissues, rhizosphere soil and soil surrounding roots of diseased trees. Fusarium oxysporum, the cause of koa dieback and wilt, was not isolated from seeds or seedpods but was found most commonly on roots and soil near diseased koa seedlings. Fusarium subglutinans was the most common species iso...

Fusarium isolates obtained from diseased koa plants, rhizosphere soil and seeds/seedcoats may or may not be pathogenic on young seedlings under greenhouse conditions. This includes isolates of F. oxysporum, the putative cause of koa wilt/dieback disease in Hawaii. We tested ten Fusarium isolates, comprising four different species, for their pathogenic potential on Acacia koa seedlings under gre...

Biotransformation of natural products by filamentous fungi is a powerful and effective approach to achieve derivatives with valuable new chemical and biological properties. Although diterpenoid substrates usually exhibit good susceptibility towards fungi enzymes, there have been no studies concerning the microbiological transformation of halimane-type diterpenoids up to now. In this work, we in...

Radix pseudostellariae is a perennial tonic medicinal plant, with high medicinal value. However, consecutive monoculture of this plant in the same field results in serious decrease in both yield and quality. In this study, a 3-year field experiment was performed to identify the inhibitory effect of growth caused by prolonged monoculture of R. pseudostellariae. DGGE analysis was used to explore ...