Cold acclimation is a critical physiological adaptation for coping with seasonal cold. By increasing their cold tolerance individuals can remain active for longer at the onset of winter and can recover more quickly from a cold shock. In insects, despite many physiological studies, little is known about the genetic basis of cold acclimation. Recently, transcriptomic analyses in Drosophila virili...

This chapter explores the occurrence and dominance of cyanobacteria in some of the harshest environments on earth, the cryosphere, where extreme cold and the near absence of liquid water provide severe constraints on growth and survival. They are present in ice-based ecosystems including snow, glacier ice, lake ice and ice-shelves, and sometimes achieve remarkably high biomass concentrations. C...

In public online discussion forums, the large user base and frequent posts can create challenges for recommending threads to users. Importantly, traditional recommender systems, based on collaborative filtering, are not capable of handling never-seen-before items (threads). We can view this task as a form of Extreme Multilabel Classification (XMLC), where for a newly-posted thread, we predict t...

Suspensions of leukemic cells of mice from three different strains of leukemia were subjected to rapid or slow freezing and rapid or slow thawing. Suspensions rapidly frozen to -196 degrees C. were in all cases innocuous, whereas those frozen slowly were capable of transmitting leukemia. The infectivity of slowly frozen material varied from an estimated 0.0001 per cent to 1 per cent of that of ...

Infants rats depend on heat production by brown adipose tissue (BAT) during cold challenge. Although it has been suggested that BAT thermogenesis protects the heart in the cold, the relationship of BAT activation to cardiac rate has not been examined directly. In the first experiment, the cardiac rate of 2- and 7- to 8-day-old rat pups was monitored during moderate and extreme cold challenge. P...

Climate change driven increases in intensity and frequency of both hot and cold extreme events contribute to coral reef decline by causing widespread coral bleaching and mortality. Here, we show that hot and cold temperature changes cause distinct physiological responses on different time scales in reef-building corals. We exposed the branching coral Acropora yongei in individual aquaria to a ±...

BACKGROUND Many studies have examined the association between ambient temperature and mortality. However, less evidence is available on the temperature effects on coronary heart disease (CHD) mortality, especially in China. In this study, we examined the relationship between ambient temperature and CHD mortality in Beijing, China during 2000 to 2011. In addition, we compared time series and tim...