Extensive stage small cell lung cancer (ES-SCLC) represents approximately half of all diagnosed small cell lung cancer worldwide. It is notorious for a high risk of local recurrence although it's sensitive to chemotherapy. Nearly 90% of intrathoracic failures happen in the first year after diagnosis. The cornerstone of treatment for ES-SCLC is etoposide-platinum based chemotherapy. Consolidativ...

the developments of the iran-iraq war scene following the iranian victory in faw which changed the balance of power in favor of iran caused the iraq not only to intensify her attacks against the residential areas and industrial circles, but also increases the using of chemical weapons during her attacks in ground battles as a deterrent factor. in other words, the iraqi decision-makers when unde...

Conjugated linoleic acid (CLA) is presently under extensive research because of its potent anticarcinogenic effects and also because of its effects on the immune system and on lipid metabolism. The biological effects of these acids are briefly reviewed. Ruminant edible products are the richest natural sources of CLA because they are supposed to be mainly derived from rumen biohydrogenation of l...

Antiviral strategies targeting hijacked cellular processes are less easily evaded by the virus than viral targets. If selective for viral functions, they can have a high therapeutic index. We used RNA trans-splicing to deliver the herpes simplex virus thymidine kinase-ganciclovir (HSV-tk/GCV) cell suicide system into HIV-producing cells. Using an extensive in silico bioinformatics and RNA struc...

The level of serum neuron-specific enolase (NSE) has been implicated as a prognostic factor for patients with small cell lung cancer (SCLC). A prospective evaluation was undertaken to assess the prognostic significance of pretreatment NSE and treatment-induced minimum NSE values in patients with SCLC. Patients from two Phase III North Central Cancer Treatment Group trials [one for patients with...

BACKGROUND The rate of detection of HER-2/neu and CD117 (c-kit) overexpression in small cell lung cancer (SCLC) has varied widely; between 5-35% and 21-70% respectively. METHODS To evaluate the relationship between pesticide exposure and HER-2/neu and CD117 overexpression in extensive stage SCLC (ESSCLC), we identified patients with ESSCLC and assessed pesticide exposure using a predetermined...

Abstract Acquiring vocabulary, as a significant and challenging part of language learning process, has always been consistent with reading. In this study, the researchers examined the effect of enhanced extensive reading on EFL learners’ incidental acquisition of English vocabulary, with specific focus on phrasal verbs. Twenty five homogenized participants were selected and divided into two gro...

Abstract Acquiring vocabulary, as a significant and challenging part of language learning process, has always been consistent with reading. In this study, the researchers examined the effect of enhanced extensive reading on EFL learners’ incidental acquisition of English vocabulary, with specific focus on phrasal verbs. Twenty five homogenized participants were selected and divided into two gro...