We report the development of homology models of dopamine (D(2), D(3), and D(4)), serotonin (5-HT(1B), 5-HT(2A), 5-HT(2B), and 5-HT(2C)), histamine (H(1)), and muscarinic (M(1)) receptors, based on the high-resolution structure of the beta(2)-adrenergic receptor. The homology models were built and refined using Prime. We have addressed the required modeling of extracellular loop 2, which is ofte...

The extent of interspecific homology between D. melanogaster and D. virilis for ribosomal RNA and ribosomal protein was examined using the techniques of two-dimensional gel electrophoresis, and RNA-DNA filter hybridization. Only 2 of the 71 ribosomal proteins resolved were found to be species specific, while comparisons of soluble larval hemolymph protein patterns showed little similarity. Depe...

The diversity of 2,4-dichlorophenoxyacetic acid (2,4-D)-degradative plasmids in the microbial community of an agricultural soil was examined by complementation. This technique involved mixing a suitable Alcaligenes eutrophus (Rifr) recipient strain with the indigenous microbial populations extracted from soil. After incubation of this mixture, Rifr recipient strains which grow with 2,4-D as the...

This is a further investigation of our approach to group actions in homological algebra the settings homology $$\Gamma $$ -simplicial groups, particularly -equivariant and cohomology -groups. new direction called -homological algebra. The abstract kernel non-abelian extensions its relationship with obstruction theory, second are extended case -extensions We compute rational (co)homology groups ...

Using ideas from persistent homology, the robustness of a level set of a real-valued function is defined in terms of the magnitude of the perturbation necessary to kill the classes. Prior work has shown that the homology and robustness information can be read off the extended persistence diagram of the function. This paper extends these results to a non-uniform error model in which perturbation...

BACKGROUND: Colibacillosis, caused by different serotypes of avian pathogenic Escherichia coli (APEC), is one of the important diseases in poultry industry. The isolate O78 is the most prevalent serotype of APEC in Iran. One of the APEC virulence factors, increased serum survival (iss) gene, is related to serum resistance. The usual form of colibacillosis in avian is extraintestinal, and serum ...

We present an algorithm for computing the homology of inclusion maps which is based on the idea of coreductions and leads to significant speed improvements over current algorithms. It is shown that this algorithm can be extended to compute both persistent homology and an extension of the persistence concept to two-sided filtrations. In addition to describing the theoretical background, we prese...

The theory of local homology modules was initiated by Matlis in 1974. It is a dual version of the theory of local cohomology modules. Mohammadi and Divaani-Aazar (2012) studied the connection between local homology and Gorenstein flat modules by using Gorenstein flat resolutions. In this paper, we introduce generalized local homology modules for complexes and we give several ways for computing ...