The cytochrome P450 enzyme superfamily (CYP), E.C. 1.14.-.-, are haem-containing monooxygenases with a vast range of both endogenous and exogenous substrates. These include sterols, fatty acids, eicosanoids, fat-soluble vitamins, hormones, pesticides carcinogens as well drugs. Listed below the human enzymes, their relationship rodent CYP activities is obscure in that species orthologue may not ...

Bacterial-fungal interactions are important in the functioning of natural ecosystems. We examined possible synergistic or antagonistic effects during degradation polycyclic aromatic hydrocarbons (PAHs) by a fungal–bacterial co-culture. Bacteria and fungi were grown liquid nutrient medium supplemented with PAH substrates. The PAHs identification metabolites checked HPLC. Enzyme activities spectr...

Francisella tularensis is classified as a category A priority pathogen and causes fatal disseminated disease in humans upon inhalation of less than 50 bacteria. Although drugs are available for treatment, they are not ideal because of toxicity and route of delivery, and in some cases patients relapse upon withdrawal. We have an ongoing program to develop novel FAS-II FabI enoyl-ACP reductase en...

ABSTRACT- This study was designed to investigate the effects of adding different levels of date presscakes (DP), with and without enzyme supplementation (ES), on the ileal digestibility and growth performance of broiler. A completely randomized design containing 2 × 5 factorial arrangement of treatments (with and without enzyme supplementation and 5 levels of DP) was used. The enzyme complex co...

Malus hupehensis is an excellent Malus rootstock species, known for its strong adverse-resistance and apomixes. In the present study, stem cuttings of M. hupehensis were treated with three types of exogenous hormones, including indole acetic acid (IAA), naphthalene acetic acid (NAA), or green growth regulator (GGR). The effects and mechanisms of exogenous hormone treatment and antioxidant enzym...

We investigated the effect of an albumin infusion on enzyme activity, expression level cytochrome P450 2E1 (CYP2E1), and oxidative stress in serum liver streptozotocin (STZ)-induced diabetic rats. The STZ treatment enhanced alanine aminotransferase aspartate activities rat compared with those untreated Treatment elevated catalytic activity CYP2E1, stress, decreased reducing potentials liver, su...

Sterol ester hydrolase (cholesterol esterase, E.C. 3.1.1.13) of bovine adrenal cortex has been extensively purified by ammonium sulfate fractionation, acid precipitation, hydroxylapatite chromatography, and Sephadex G-200 chromatography. During the purification sequence, the hydrolase activity was purified free of endogenous protein kinase. With this purified preparation, activation by cyclic A...

Accumulation of urocanic acid (UCA) in stored fish has been attributed to both endogenous and exogenous histidine ammonia lyase (HAL) activity. The level HAL Indian mackerel, tuna, sardine were monitored at different temperatures. It was also evaluated during storage eviscerated whole under vacuum packaging. UCA production storage. highest the lowest activity fresh observed mackerel tuna (26.32...