Exertional dyspnea limits exercise in some mitochondrial myopathy (MM) patients, but the clinical features of this syndrome are poorly defined, and its underlying mechanism is unknown. We evaluated ventilation and arterial blood gases during cycle exercise and recovery in five MM patients with exertional dyspnea and genetically defined mitochondrial defects, and in four control subjects (C). Pa...

Case Presentation A 65 year-old Caucasian male originally presented to an outside hospital complaining of worsening paroxysmal nocturnal dyspnea, orthopnea, and recent exertional chest pain associated with dyspnea. The patient’s past medical history was significant for coronary artery disease status post coronary bypass, severe aortic stenosis status post bioprosthetic aortic valve repair, cong...

Upper airway obstruction due to subglottic mass can be misdiagnosed. We report the case of a 66-year-old man who was treated for chronic obstructive pulmonary disease (COPD) before a diagnosis of pleomorphic adenoma of the subglottis was made. According to the history of chronic cough and exertional dyspnea, he was treated with inhaled corticosteroids for COPD. Bronchoscopy and computed tomogra...

Swyer-James syndrome was first described in 1953 as unilateral pulmonary emphysema in a 6-year-old boy. The characteristic feature of this syndrome is unilateral pulmonary hyperlucency on a chest X-ray film. Typical symptoms include recurrent chest infections, chronic cough, wheezing, and exertional dyspnea. Although there have been a few reports of pneumothorax in patients with Swyer-James syn...

Pulmonary and cardiocirculatoiy function were studied in 21 ambulatory patients with rheumatic heart disease. A pattern of pulmonary function was observed which deviated from normal to a degree insufficient to account for the exertional dyspnea of these patients. The pathogenesis of this symptom is, therefore, discussed in relation to the observed cardiocirculatory abnormalities which were ofte...

Patient: Male, 60 Final Diagnosis: Iatrogenic intercostal lung hernia Symptoms: - Medication: No medication Clinical Procedure: Surgically cerrected Specialty: Thoracic surgery. OBJECTIVE Unusual clinical course. BACKGROUND Iatrogenic intercostal lung hernia is a rare thoracic pathology. Injury of...

PURPOSE The purpose of this study was a) to compare the effect of three different warm-up protocols upon rowing performance and perception of dyspnea, and b) to identify the functional significance of a respiratory warm-up. METHODS A group of well-trained club rowers (N = 14) performed a 6-min all-out rowing simulation (Concept II). We examined differences in mean power output and dyspnea mea...

A 51-yr-old man presented exertional dyspnea as a consequence of iliocaval fistula combined with paradoxical pulmonary embolism and high-output heart failure. Endovascular stent-graft repair was performed to cover iliocaval fistula and restore the heart function. After the procedure, dyspnea was improved and procedure related complication was not seen. A 6-month follow-up computed tomography sh...

To evaluate the effects of current supportive care measures for the adult respiratory distress syndrome (ARDS) upon the upper airway, we studied 30 survivors of ARDS. All patients were interviewed and examined and performed inspiratory and expiratory maximal flow-volume curves more than six months after the onset of ARDS. Three women had developed symptomatic upper airway obstruction due to lar...

Exercise intolerance is a feature of chronic heart failure (CHF). We hypothesized that excessive loading of the respiratory muscle pump might contribute to exertional breathlessness. One marker of excessive muscle-loading is slowing of maximum relaxation rate (MRR) and, therefore, to test our hypothesis, we investigated the effect of exhaustive treadmill walking on inspiratory muscle MRR in pat...