BACKGROUND Children who suffer from recurrent wheezy episodes are often promptly classified as asthmatic. The aim of this study was to evaluate a population of mild wheezy children with repeatedly normal spirometric tests at rest for atopy, bronchial hyperresponsiveness, and peak expiratory flow variability. METHODS Thirty nine children aged 6-16 years with 1-12 wheezy attacks during the prev...

look at first glance as though ICI 118 551 has no effect on exercise-induced hyperkalaemia compared with placebo. However, the baseline potassium concentration was significantly lower in the ICI 118 551 group than in the placebo group, and this may explain the apparent lack of effect on exercise response. Furthermore, in that study atenolol had no effect on the exercise-induced potassium respon...

OBJECTIVE To assess the repeatability and validity of the IUATLD respiratory symptoms questionnaire in relation to exercise-induced bronchoconstriction or bronchodilator responses in a community in southern Ethiopia. DESIGN A case-control study. SETTING Rural and small town setting in southern Ethiopia, April to May 2006. SUBJECTS Two hundred and forty seven adults and children who previo...

BACKGROUND There are large differences in the prevalence of atopic disease between urban and rural areas of developing countries, without good explanation. Diet has been associated with atopic disease, but studies of specific nutrients are contradictory, cross-sectional studies often being unsupported by trials. We investigated diet as an explanation for the difference in the prevalence of atop...